Results 141 to 150 of about 500,404 (395)

Prophylactic phenylephrine and fluid co‐administration to reduce spinal hypotension during elective caesarean section in a resource‐limited setting: a prospective alternating intervention study [PDF]

, 2019
A. S. Buthelezi, David G. Bishop, Reitze Rodseth, Robert A. Dyer   +3 more
openalex   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses and Dose Titration of Bexicaserin in Healthy Participants in a Randomized, Double‐Blind, Placebo‐Controlled Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams, Rosa Chan, Chad Orevillo, Gale O'Connell, Dewey McLin, Shikha Polega, Nuggehally R. Srinivas, Randall Kaye   +7 more
wiley   +1 more source

Heat and Dehydration Additively Enhance Cardiovascular Outcomes following Orthostatically-Stressful Calisthenics Exercise

Frontiers in Physiology, 2017
Exercise and exogenous heat each stimulate multiple adaptations, but their roles are not well delineated, and that of the related stressor, dehydration, is largely unknown.
Ashley P. Akerman, Ashley P. Akerman, Samuel J. E. Lucas, Samuel J. E. Lucas, Rajesh Katare, James D. Cotter   +5 more
doaj   +1 more source

Pulse transit time confirms altered response to spinal anaesthesia in pregnancy induced hypertension [PDF]

, 2011
Poster presented at the International Society for the Study of Hypertension in Pregnancy (ISSHP)Congress, Toronto 2002.Part of the Portfolio Thesis by Geoffrey H.
Bruce, J., Drummond, G., Sharwood-Smith, Geoffrey H.   +2 more
core  

Iatrogenic Spinal Cord Injury Resulting From Cervical Spine Surgery. [PDF]

, 2017
STUDY DESIGN: Retrospective cohort study of prospectively collected data. OBJECTIVE: To examine the incidence of iatrogenic spinal cord injury following elective cervical spine surgery.
Arnold, Paul M., Buser, Zorica, Currier, Bradford L., Daniels, Alan H., Fehlings, Michael G., Fish, David E., Hart, Robert A., Hilibrand, Alan S., Lord, Elizabeth L., Mroz, Thomas E., Nassr, Ahmad, Riew, K. Daniel, Sebastian, Arjun S., Stroh, D. Alex, Tortolani, P. Justin, Wang, Jeffrey C.   +15 more
core   +2 more sources

Neurochemistry of neurons in the ventrolateral medulla activated by hypotension: Are the same neurons activated by glucoprivation? [PDF]

, 2017
Lindsay M. Parker, Sheng Le, Travis Wearne, Kate Louise Hardwick, Natasha N. Kumar, Katherine J. Robinson, Simon McMullan, Ann K. Goodchild   +7 more
openalex   +1 more source

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel, Filippa Schreeck, Simon Jaeger, Severin Schricker, Elke Schaeffeler, Svitlana Igel, Daniela Steinberger, Manuel Pagitz, Jörg Latus, Markus Ketteler, Kerstin Bühl, Marc‐H. Dahlke, Hans‐Georg Kopp, Matthias Schwab   +13 more
wiley   +1 more source

The Prevalence of Orthostatic Hypotension: A Systematic Review and Meta-Analysis

The journals of gerontology. Series A, Biological sciences and medical sciences, 2018
Background Orthostatic hypotension (OH) is associated with increased risk of falls, cognitive impairment and death, as well as a reduced quality of life. Although it is presumed to be common in older people, estimates of its prevalence vary widely.
N. Saedon, Maw Pin Tan, J. Frith
semanticscholar   +1 more source

Transthyretin amyloid cardiomyopathy: Literature review and red‐flag symptom clusters for each cardiology specialty

ESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.
Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya, Toru Kubo, Jin Endo, Seiji Takashio, Masatoshi Minamisawa, Jun Hamada, Tomonori Ishii, Hajime Abe, Hiroaki Konishi, Kenichi Tsujita   +9 more
wiley   +1 more source

Postural hypotension

BMJ, 2021
Artaza Gilani, Stephen P Juraschek, Matthew J Belanger, Julie E Vowles, S Goya Wannamethee   +4 more
openaire   +3 more sources