Results 141 to 150 of about 308,666 (390)
Association of mortality risk with various definitions of intradialytic hypotension.
Journal of the American Society of Nephrology, 2015 Intradialytic hypotension is a serious and frequent complication of hemodialysis; however, there is no evidence-based consensus definition of intradialytic hypotension.
Jennifer E. Flythe +4 more
semanticscholar +1 more source
Dose Determinations at Drug Approval Reviews: FDA‐Approved Drugs in Past 5 Years
Clinical Pharmacology &Therapeutics, EarlyView.Drug dose appropriateness is one of the most discussed issues in regulatory reviews. We analyzed dose determinations during Food and Drug Administration (FDA) drug reviews to determine whether there were changes between the proposed and approved doses of new molecular entities (NMEs), including cases where postmarketing dose‐finding studies were ...
Sachiko Mita, Shunsuke Ono
wiley +1 more source
POSTANESTHETIC HYPOTENSION FOLLOWING CYCLOPROPANE [PDF]
, 1953 Joseph J. Buckley +5 more
openalex +1 more source
Personalizing the Definition of Hypotension to Protect the Brain.
Anesthesiology, 2019 Originally championed by Harvey Cushing in the early 1900s, the measurement of blood pressure during anesthesia and surgery became widespread in the 1920s. Physicians soon recognized the relationship between intraoperative hypotension and adverse patient
K. Brady +5 more
semanticscholar +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.This study aimed to analyze differences in the exposure‐response relationship for factor Xa inhibitors (FXaI) between patients aged ≥ 80 and < 80 years. Patients with atrial fibrillation (AF) taking rivaroxaban, apixaban, or edoxaban were enrolled, and a single steady‐state trough concentration was measured.
Shin‐Yi Lin +7 more
wiley +1 more source
Placental pathology and neonatal encephalopathy
International Journal of Gynecology &Obstetrics, Volume 160, Issue 1, Page 22-27, January 2023., 2023 Abstract Neonatal encephalopathy (NE) is an important cause of neonatal morbidity and mortality worldwide; however, there remain gaps in our knowledge about its pathogenesis. The placenta has been implicated in the pathogenesis of this disease but conclusive evidence related to the placental factors that influence it is sparse.
Aine Fox +3 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.The study presents a validated UPLC‐MS/MS method applied for the detection of fentanyl, NPFs, xylazine, nitazenes in hair samples from 250 post‐mortem cases collected at the Jefferson County Coroner/Medical Examiner's Office (Birmingham, AL, USA). In 52% of the analyzed hair samples, fentanyl, its main metabolites, and related analogs were detected ...
Marco Ballotari +6 more
wiley +1 more source
Health Technology Assessment, 2009 Objectives: To assess the effects of acute pressor and depressor blood pressure (BP) manipulation on 2-week death and dependency following acute stroke and investigate the safety and efficacy of such treatments.
J Potter +8 more
doaj +1 more source
Frontiers in Physiology, 2017 Exercise and exogenous heat each stimulate multiple adaptations, but their roles are not well delineated, and that of the related stressor, dehydration, is largely unknown.
Ashley P. Akerman +5 more
doaj +1 more source