Results 31 to 40 of about 303,510 (300)
Hypothalamic releasing and inhibiting hormones
Distinct substances have been prepared from hypothalamic extracts of several species including man, which in minute amounts stimulate the release of thyrotropin, growth hormone, follicle-stimulating hormone and luteinizing hormone, and inhibit the ...
Kastin, Abba J, Schally, Andrew V
core +1 more source
Activation of mammalian target of rapamycin 1 (mTORC1) by nutrients, insulin and leptin leads to appetite suppression (anorexia). Contrastingly, increased AMP-activated protein kinase (AMPK) activity by ghrelin promotes appetite (orexia).
Kenneth R. Watterson +6 more
doaj +1 more source
Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali +4 more
wiley +1 more source
Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neurons. [PDF]
Some pathological conditions with feeding pattern alterations, including obesity and Huntington disease (HD) are associated with hypothalamic dysfunction and neuronal cell death. Additionally, the hypothalamus is a neurogenic region with the constitutive
Lígia Sousa-Ferreira +7 more
doaj +1 more source
Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli +13 more
wiley +1 more source
The organisational effects of adolescent gonadal hormones on behavioural development in rats [PDF]
Gonadal steroid hormones play an important role in adolescent neural and behavioural development, causing changes that can be seen throughout life. Endogenous hormones have a direct impact on behaviour in both immediate and permanent ways by acting on ...
Kulbarsh, Kyle D.
core +2 more sources
Male reproduction is governed by the classical hypothalamo-hypophyseal testicular axis: Hypothalamic gonadotropin releasing hormone (GnRH), pituitary luteinizing hormone (LH) and follicle stimulating hormone (FSH) and the gonadal steroid, principally ...
Anand Kumar +2 more
doaj +1 more source
Interaction of glucose sensing and leptin action in the brain
Background: In response to energy abundant or deprived conditions, nutrients and hormones activate hypothalamic pathways to maintain energy and glucose homeostasis. The underlying CNS mechanisms, however, remain elusive in rodents and humans.
Rosa J.W. Li +2 more
doaj +1 more source
Hypothalamic hormones a.k.a. hypothalamic releasing factors [PDF]
Originally searched for and eventually isolated as factors of hypothalamic origin controlling anterior pituitary secretions, these hypophysiotropic peptides are now a chapter of physiology and medical endocrinology of their own. Defying the concept of ‘neuropeptides’ they and their receptors are now known to be ubiquitous and to have subtle as well as ...
openaire +2 more sources
Different Responses to Two Hypothalamic Hormones in Acromegalics
It is now well established that hypothalamic hormones stimulate the release of all the known hormones from the anterior pituitary gland except prolactin which is primarily under an inhibitory influence.1 The hypothalamus also inhibits the release of ...
Kastin, Abba J +5 more
core +1 more source

