Results 211 to 220 of about 3,614,670 (301)

The Real‐World Safety Profile of Haloperidol: A Comprehensive Pharmacovigilance Analysis Using the Large‐Scale FAERS Database

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
This first comprehensive FAERS‐based pharmacovigilance analysis of haloperidol over two decades characterized the real‐world safety profile across 9916 reports. Strong signals were found for nervous, psychiatric, and cardiac disorders. Known risks were confirmed and novel signals revealed. Sex‐ and age‐specific vulnerabilities were identified. Findings
Nengping Luo, Lu Xiao, Ying Liu, Xiang Liu   +3 more
wiley   +1 more source

Safety and Efficacy of Therapeutic Hypothermia in Traumatic Spinal Cord Injury Management: A Systematic Review and MetaAnalysis. [PDF]

Arch Acad Emerg Med
Fahim F, Mehmandoost M, Karami Dehkordi P, Khorram A, Heshmaty S, Zolfaghari F, Ghamarpour M, Oveisi S, Seddighi AS, Zali A.   +9 more
europepmc   +1 more source

A single‐cell census of pulmonary endarterectomies tissue across different anatomical regions in chronic thromboembolic pulmonary hypertension

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
This study provides the first intra‐individual, regional single‐cell comparison of main/lobar versus bifurcate pulmonary endarterectomy (PEA) specimens. It reveals distinct macrophage polarisation, divergent T‐cell compositions and pronounced smooth muscle cell (SMC)‐to‐myofibroblast transition in the bifurcate region. These findings highlight regional
Rui Zhang, Yunlong Zhang, Huiting Li, Jing Zhang, Shou Han, Xinbo Cheng, Qinhua Zhao, Jing He, Cijun Luo, Hongling Qiu, Jianfeng Zhang, Sugang Gong, Lan Wang   +12 more
wiley   +1 more source

A Rare Case of Hypothermia Due to Quetiapine Use. [PDF]

Cureus
Mogulla SM, Kamatam S.
europepmc   +1 more source

From the lethal triad to the lethal diamond and beyond: An AI‐augmented perspective on modern hemostatic resuscitation

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 5, October 2026.
Abstract Background Uncontrolled hemorrhage remains the leading cause of preventable mortality in both civilian and military trauma sectors. The paradigm of resuscitation has decisively shifted from aggressive crystalloid administration to Damage Control Resuscitation, centering on early hemostatic control and the mitigation of the “Lethal Diamond ...
Jonghee Han, Junepill Seok, Su Young Yoon, Jin‐Uk Choi, Jin Suk Lee, Younghoon Sul   +5 more
wiley   +1 more source

Predictors for intrapartum cesarean delivery after labor induction for suspected fetal growth restriction at term

International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 249-256, October 2026.
Abstract Objective In term pregnancies with suspected fetal growth restriction (FGR) undergoing induction of labor (IOL), predictors for intrapartum cesarean delivery (CD) remain unclear. We aimed to determine predictors for intrapartum CD in this population. Methods This study included a retrospective cohort of singleton pregnancies undergoing IOL at ≥
Matan Anteby, Yael Reichman, Alon Bar‐Or, Jacky Herzlich, Stav Cohen, Karina Krajden Haratz, Anat Lavie, Liran Hiersch, Yariv Yogev   +8 more
wiley   +1 more source

A human 3D BBB chip model of acute stroke simulating a reversible penumbra. [PDF]

PLoS One
Kwak KA, Shin EY, Yi KS, Choi CH.
europepmc   +1 more source

Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia

iMeta, Volume 5, Issue 5, October 2026.
Severe Klebsiella pneumoniae pneumonia combines intense inflammation with failure to control infection, yet the cellular basis is unclear. Using a severity‐focused single‐cell atlas of 708,894 peripheral blood mononuclear cells from 100 individuals, complemented by plasma protein measurements and flow cytometry, we show that disease severity redirects ...
Hongquan Chen, Xiaoling Wang, Xiang Liu, Kui Dong, Yanying Feng, Min Yuan, Shiyi Wang, Fangfang Fan, Yong Tian, Zhiming Kang, Xiushuai Du, Chaolu Hasi, Hong Lu, Wei Guan, Xu Chen, Mengyu Cheng, Wei Wei, Nan Guo, Zhiguo Liu, Xiaotong Qiu, Yiwei Shi, Kun Xiao, Yi Wang, Zhenjun Li   +23 more
wiley   +1 more source

Adjunctive mild controlled hypothermia for moderate necrotizing enterocolitis in very low birth weight infants: a prospective cohort study with external contemporaneous controls. [PDF]

Eur J Pediatr
Gonçalves-Ferri WA, Sarri VC, Ferreira CHF, Vidoto Martins ME, Nogueira BT, Meneses J, Matsushita FY, Marques L M Ferreira D, do Vale MS, de Jesus H Nader P, Pegoraro G Melo F, de Moura MDR, Mussi-Pinhata MM, Aragon DC.   +13 more
europepmc   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng, Yuanyuan Shen, Ying Sun, Lu Lu, Chongkui Sun   +4 more
wiley   +1 more source