Results 31 to 40 of about 153,410 (301)
Hypothermia and heart rate variability in a healthy newborn piglet model
Scientific Reports, 2022 Decreased heart rate variability (HRV) may be a biomarker of brain injury severity in neonatal hypoxic-ischemic encephalopathy for which therapeutic hypothermia is standard treatment. While therapeutic hypothermia may influence the degree of brain injury;
Mette Vestergård Pedersen +4 more
doaj +1 more source
Short- and Long-Term Outcomes in Very Low Birth Weight Infants with Admission Hypothermia. [PDF]
PLoS ONE, 2015 Neonatal hypothermia remains a common problem and is related to elevated morbidities and mortality. However, the long-term neurodevelopmental effects of admission hypothermia are still unknown.
Hung-Yang Chang +8 more
doaj +1 more source
Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog [PDF]
Eur J Pharmacol, 173174 (2020), 2020 Neurotensin (NT) exerts naloxone-insensitive antinociceptive action through its binding to both NTS1 and NTS2 receptors and NT analogs provide stronger pain relief than morphine on a molecular basis. Here, we examined the analgesic/adverse effect profile of a new NT(8-13) derivative denoted JMV2009, in which the Pro10 residue was substituted by a ...
arxiv +1 more source
Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia.
New England Journal of Medicine, 2002 BACKGROUND Cardiac arrest outside the hospital is common and has a poor outcome. Studies in laboratory animals suggest that hypothermia induced shortly after the restoration of spontaneous circulation may improve neurologic outcome, but there have been ...
Stephen A Bernard +6 more
semanticscholar +1 more source
Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest.
New England Journal of Medicine, 2002 BACKGROUND Cardiac arrest with widespread cerebral ischemia frequently leads to severe neurologic impairment. We studied whether mild systemic hypothermia increases the rate of neurologic recovery after resuscitation from cardiac arrest due to ...
Ashkan Mohammad H. Marissa Patrick Kara Alex Laurie Ali H Afshin Forouzanfar Reitsma Sur Estep Lee Marczak M +153 more
semanticscholar +1 more source
Effects of Methylprednisolone on Neuroprotective Effects of Delay Hypothermia on Spinal Cord Injury in Rat [PDF]
Asian Spine Journal, 2015 Study DesignA retrospective study.PurposeThe aim of this study was to evaluate the effects of delayed hypothermia on spinal cord injuries in rats. In addition, the effect of methylprednisolone on therapeutic window of hypothermia was evaluated.Overview ...
Saeid Karamouzian +3 more
doaj +1 more source
Intensive Care Medicine Experimental, 2022 Background Sedatives and mild hypothermia alone may yield neuroprotective effects in acute ischemic stroke (AIS). However, the impact of this combination is still under investigation.
Denise Battaglini +12 more
doaj +1 more source
Acta Biomedica Scientifica, 2021 Background. Newborn infants who have undergone severe birth asphyxia have a high risk of neurological disorders and death. The most effective method for the treatment of hypoxic ischemic encephalopathy caused by intrapartum asphyxia is therapeutic ...
A. A. Zarubin +4 more
doaj +1 more source
Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy.
New England Journal of Medicine, 2005 BACKGROUND Hypothermia is protective against brain injury after asphyxiation in animal models. However, the safety and effectiveness of hypothermia in term infants with encephalopathy is uncertain. METHODS We conducted a randomized trial of hypothermia
S. Shankaran +19 more
semanticscholar +1 more source
Hypothermia in Preterm Infants in the First Hours after Birth: Occurrence, Course and Risk Factors. [PDF]
PLoS ONE, 2016 Hypothermia is associated with increased morbidity and mortality rates. Preterm infants frequently have hypothermia when they are admitted to the NICU, but there is no data on the occurrence of hypothermia during the first hours after admission.To ...
Arenda Mank +5 more
doaj +1 more source