Results 31 to 40 of about 77,030 (217)

Cold blood perfusion for selective hypothermia in acute ischemic stroke

open access: yesBrain Circulation, 2019
Hypothermia is the most reliably effective neuroprotectant, and yet systemic complications limit application. A large body of animal data suggests that hypothermia is effective for focal cerebral ischemia, namely acute ischemic stroke.
Thomas K Mattingly, Stephen P Lownie
doaj   +1 more source

A Cryopreservation‐Based Supply Chain Strategy for Extrusion Bioprinting in Space

open access: yesAdvanced Materials Technologies, EarlyView.
Extrusion bioprinting on crewed space platforms requires a bioink that stays functional along the logistic chain. Here, cells and biomaterial ink travel separately, the cells cryopreserved and the ink cold stored, and are combined only minutes before printing.
Johannes Windisch   +7 more
wiley   +1 more source

Induced Hypothermia Does Not Harm Hemodynamics after Polytrauma: A Porcine Model

open access: yesMediators of Inflammation, 2015
Background. The deterioration of hemodynamics instantly endangers the patients’ life after polytrauma. As accidental hypothermia frequently occurs in polytrauma, therapeutic hypothermia still displays an ambivalent role as the impact on the ...
Matthias Weuster   +10 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Relation between initial hypothermia, course of the hypothermia and mortality in patients with septic shock: a post-hoc analysis of the SEPSISPAM randomized trial

open access: yesAnnals of Intensive Care
Background: In patients with septic shock as well as in the critically ill, the impact of hypothermia and core temperature changes during the first 24 h on mortality remains uncertain. In this post-hoc analysis of the SEPSISPAM trial, we investigated the
Louis Bordeau   +33 more
doaj   +1 more source

Cardioprotective effect of combination therapy by mild hypothermia and local or remote ischemic preconditioning in isolated rat hearts

open access: yesScientific Reports, 2021
A multitargeted strategy to treat the consequences of ischemia and reperfusion (IR) injury in acute myocardial infarction may add cardioprotection beyond reperfusion therapy alone.
Marie V. Hjortbak   +9 more
doaj   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

open access: yesAdvanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma   +14 more
wiley   +1 more source

The Effect of Postinduction Blood Glucose on Intraoperative Hypothermia

open access: yesMedicina, 2023
Background and Objectives: Hypothermia frequently occurs in patients undergoing surgery and is associated with adverse complications. Therefore, this study aimed to investigate the postinduction blood glucose and occurrence of intraoperative hypothermia ...
Zhangtian Shen   +2 more
doaj   +1 more source

Soft Hypoxia‐Adaptive Bioelectronics Integrating PEDOT:PSS/Polydopamine/Enzyme Biocomposites for Closed‐Loop Therapeutics of Chronic Wounds

open access: yesAdvanced Science, EarlyView.
Hypoxia‐adaptive bioelectronics based on poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/polydopamine (PDA)/enzyme biocomposites couple O2‐centric biosensing with embedded O2 therapy to address oxygen‐deficient chronic wounds. Local O2 provision restores enzyme‐based metabolite sensing, while catalase‐mediated oxygen generation and
Songrui Liu   +16 more
wiley   +1 more source

2023 Chinese Expert Consensus Statement for Prevention and Management of Perioperative Hypothermia

open access: yesXiehe Yixue Zazhi, 2023
The 2023 Chinese Expert Consensus Statement for Prevention and Management of Perioperative Hypothermia is an update of the 2017 Chinese Expert Consensus Statement for Prevention and Management of Perioperative Hypothermia.
National Center for Quality Assurance of Anesthesia
doaj   +1 more source

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