Results 61 to 70 of about 244,003 (397)

Cold blood perfusion for selective hypothermia in acute ischemic stroke

Brain Circulation, 2019
Hypothermia is the most reliably effective neuroprotectant, and yet systemic complications limit application. A large body of animal data suggests that hypothermia is effective for focal cerebral ischemia, namely acute ischemic stroke.
Thomas K Mattingly, Stephen P Lownie
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Data on the gene expression of cardiomyocyte exposed to hypothermia

Data in Brief, 2016
Hypothermia is widely used in neurosurgery and cardiac surgeries. However, little is known about the underlying molecular mechanisms. We previously reported that the transcriptome responses of cardiomyocyte exposed to hypothermia, “The transcriptome ...
Jian Zhang, Xiaodong Xue, Yinli Xu, Yuji Zhang, Zhi Li, Huishan Wang   +5 more
doaj   +1 more source

Natural product P57 induces hypothermia through targeting pyridoxal kinase

Nature Communications, 2023
Induction of hypothermia during hibernation/torpor enables certain mammals to survive under extreme environmental conditions. However, pharmacological induction of hypothermia in most mammals remains a huge challenge.
Ruina Wang, Lei Xiao, Jianbo Pan, Guangsen Bao, Yunmei Zhu, Di Zhu, Jun Wang, Chengfeng Pei, Qinfeng Ma, Xian Fu, Ziruoyu Wang, Mengdi Zhu, Guoxiang Wang, Ling Gong, Qiuping Tong, Min Jiang, Junchi Hu, Miao He, Yun Wang, Tiejun Li, Chunmin Liang, Wei Li, Chunmei Xia, Zengxia Li, Dengke K. Ma, Minjia Tan, Jun Yan Liu, Wei Jiang, Cheng Luo, Biao Yu, Yongjun Dang   +30 more
doaj   +1 more source

Magnetic Bioprinting and Actuation of Stretchable Muscle Tissue

Advanced Healthcare Materials, EarlyView.
Human and murine myoblasts labeled with iron oxide nanoparticles are magnetically bioprinted into wrench‐shaped tissues, which are then anchored between two magnetic needles. Mechanical stretching of these tissues enhances both their maturation and functional performance. Abstract Engineering tissues with precise, long‐lasting shapes and the capability
Noam Demri, Lise Morizur, Simon Dumas, Giacomo Gropplero, Cécile Martinat, Stéphanie Descroix, Claire Wilhelm   +6 more
wiley   +1 more source

Neuroprotective Properties of Xenon. [PDF]

, 2020
Xenon is a rare noble gas that was introduced into clinical practice more than 70 years ago. Xenon's clinical properties are predicated by its ability to fit into preformed cavities of macromolecules thereby altering their biological functions.
Laitio, Timo, Maze, Mervyn
core  

The Effect of Postinduction Blood Glucose on Intraoperative Hypothermia

Medicina, 2023
Background and Objectives: Hypothermia frequently occurs in patients undergoing surgery and is associated with adverse complications. Therefore, this study aimed to investigate the postinduction blood glucose and occurrence of intraoperative hypothermia ...
Zhangtian Shen, Kosuke Kuroda, Hiroshi Morimatsu   +2 more
doaj   +1 more source

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

Advanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno, Andrea Escudero, Oscar Ferreira Silvestre, José Manuel Terrés, Mónica Gorbe, Eva Garrido, Carlos Renero‐Lecuna, Judith Langer, María Alfonso, Javier Ibañez, Félix Sancenón, Roberto Cao‐Milán, Luis M. Liz‐Marzán, Alba García‐Fernández, Andy Hernández‐Montoto, Ramón Martínez‐Máñez   +15 more
wiley   +1 more source

Inkjet Printed Heating Elements on Textile Substrate for Functionalized Gloves

Advanced Materials Interfaces, EarlyView.
This paper focuses on the implementation of a thin‐film heating structure dedicated to a human hand form using the inkjet printing technology, on a textile substrate for the application area of flexible wearable technologies. The heating performance of the finger structures on the textile substrate demonstrated comparable stable and homogeneous heating
Kalyan Y. Mitra, Tobias Richter, Rodion Podkowyrin, Georg Buchecker, Dana Mitra, Wolfgang Kilian, Michael Eichhorst, Ralf Zichner, Stephan Odenwald   +8 more
wiley   +1 more source

Cardioprotective effect of combination therapy by mild hypothermia and local or remote ischemic preconditioning in isolated rat hearts

Scientific Reports, 2021
A multitargeted strategy to treat the consequences of ischemia and reperfusion (IR) injury in acute myocardial infarction may add cardioprotection beyond reperfusion therapy alone.
Marie V. Hjortbak, Nichlas R. Jespersen, Rebekka V. Jensen, Thomas R. Lassen, Johanne Hjort, Jonas A. Povlsen, Nicolaj B. Støttrup, Jakob Hansen, Derek J. Hausenloy, Hans Erik Bøtker   +9 more
doaj   +1 more source