Results 81 to 90 of about 96,735 (299)

Effects of mild hypothermia therapy on the levels of glutathione in rabbit blood and cerebrospinal fluid after cardiopulmonary resuscitation [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2015
Objective(s): The aim of this study wasto investigate the effects of mild hypothermia therapy on oxidative stress injury of rabbit brain tissue after cardiopulmonary resuscitation (CPR).
Hui Zhao, Yueliang Chen
doaj  

The RNA-binding protein RBM3 is involved in hypothermia induced neuroprotection

open access: yesNeurobiology of Disease, 2011
Induced hypothermia is the only therapy with proven efficacy to reduce brain damage after perinatal asphyxia. While hypothermia down-regulates global protein synthesis and cell metabolism, low temperature induces a small subset of proteins that includes ...
Sophorn Chip   +6 more
doaj   +1 more source

A Physiologically Based Modeling Approach to Evaluate Intravenous Levetiracetam Dosing in Term and Preterm Neonates

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Seizures are the most common neurologic emergency in neonates and are associated with significant morbidity and mortality. Current first‐line pharmacotherapy, phenobarbital, is associated with serious adverse effects, including impairment of the developing brain.
Alexis Johnson   +4 more
wiley   +1 more source

Interhospital variation in the management of Brief Resolved Unexplained Events (BRUE) in infants: A Canadian multicenter cohort study

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background Guidelines on Brief Resolved Unexplained Event (BRUE) only provide recommendations for infants categorized at lower risk. However, most infants fall into the higher‐risk category, leaving management decisions to individual clinicians and contributing to variation in care.
Nassr Nama   +18 more
wiley   +1 more source

Pre‐operative transcranial Doppler ultrasound assessment of cerebral collateral circulation in children undergoing veno‐arterial extracorporeal membrane oxygenation or cardiac surgery

open access: yesJournal of Medical Radiation Sciences, EarlyView.
A pre‐cannulation survey of the circle of Willis (CoW) using transcranial Doppler (TCD) ultrasound was implemented to assess cerebral collateral circulation in children undergoing VA ECMO or cardiac surgery with cervical cannulation. The technique, in use since 2019, employs high‐end ultrasound platforms to assess brain morphology, haemorrhage and ...
Tristan Reddan   +3 more
wiley   +1 more source

Neonatal Thrombocytopenia after Perinatal Asphyxia Treated with Hypothermia: A Retrospective Case Control Study

open access: yesInternational Journal of Pediatrics, 2014
Our objective was to estimate the effect of therapeutic hypothermia on platelet count in neonates after perinatal asphyxia. We performed a retrospective case control study of all (near-) term neonates with perinatal asphyxia admitted between 2004 and ...
N. Boutaybi   +6 more
doaj   +1 more source

Symptoms of egg yolk‐associated food protein‐induced enterocolitis syndrome appear following prolonged cessation

open access: yesJPGN Reports, EarlyView.
Abstract Food protein‐induced enterocolitis syndrome (FPIES) is a nonimmunoglobulin E (IgE)‐mediated food allergy. Most patients with solid FPIES experience a period of asymptomatic intake of the causative foods before onset. This study aimed to elucidate the pattern of egg yolk (EY) ingestion that triggers FPIES.
Yuka Okura   +3 more
wiley   +1 more source

Hypothermia in preterm infants admitted to low-resource neonatal units in northern Nigeria: an observational study of occurrence and risk factors

open access: yesBMC Pediatrics
Background Hypothermia is an important cause of morbidity and mortality among preterm and low-birth-weight neonates. In resource-constrained settings, limited referral infrastructure and technologies for temperature control potentiate preterm hypothermia.
Usman Abiola Sanni   +17 more
doaj   +1 more source

Limited Therapeutic Time Windows of Mild-to-Moderate Hypothermia in a Focal Ischemia Model in Rat

open access: yesStroke Research and Treatment, 2011
Although many studies have shown the great potential of induced hypothermia in stroke treatment, we recognize that there are limitations to the protective effects of hypothermia even in the laboratory.
Heng Zhao, Gary Steinberg
doaj   +1 more source

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