Results 81 to 90 of about 153,410 (301)
Advanced Science, EarlyView.This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du +13 more
wiley +1 more source
Grading the severity of hypoxic-ischemic encephalopathy in newborn EEG using a convolutional neural network [PDF]
arXiv, 2020 Electroencephalography (EEG) is a valuable clinical tool for grading injury caused by lack of blood and oxygen to the brain during birth. This study presents a novel end-to-end architecture, using a deep convolutional neural network, that learns hierarchical representations within raw EEG data.
arxiv
Therapeutic Hypothermia and Temperature Management, 2019 Three decades of animal studies have reproducibly shown that hypothermia is profoundly cerebroprotective during or after a central nervous system (CNS) insult.
Travis C. Jackson, P. Kochanek
semanticscholar +1 more source
Advanced Science, EarlyView.Annexin A3 (ANXA3) plays an endogenous protective role in endothelial dysfunction in sepsis by stabilizing the actin cytoskeleton, modulating cell permeability, and inhibiting pATF2/CD62E inflammatory signaling. Abstract Increased endothelial permeability and a dysregulated inflammatory response play key roles in organ damage in sepsis.
Manyu Xing +4 more
wiley +1 more source
Circulation, 2019 Background: Experimental trials suggest improved outcome by mild therapeutic hypothermia for cardiogenic shock after acute myocardial infarction. The objective of this study was to investigate the hemodynamic effects of mild therapeutic hypothermia in ...
G. Fuernau +14 more
semanticscholar +1 more source
Delayed Transplantation of Neural Stem Cells Improves Initial Graft Survival after Stroke
Advanced Science, EarlyView.Delayed transplantation of human iPSC‐derived neural progenitor cells (NPCs) enhances graft survival, proliferation, and axonal sprouting after stroke. Using bioluminescence imaging and histology in a mouse model of stroke, it is shown that NPC delivery at 7 days post‐stroke is more effective than acute transplantation, highlighting the importance of ...
Rebecca Z Weber +6 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.This retrospective study investigated risk factors for surgical site infections (SSIs) in right‐sided colon cancer surgeries using intracorporeal anastomosis (IA). The results demonstrated that preoperative oral antibiotics (OA) significantly reduced SSI rates, with OA identified as an independent protective factor, suggesting its beneficial role in ...
Naoya Ozawa +8 more
wiley +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.We demonstrate the direct‐laser patterning of a gold thin film on polymethyl methacrylate to fabricate a temperature sensor for dentures. The temperature sensor‐embedded smart dentures are evaluated in an oral environment, enabling in‐situ monitoring for elderly healthcare.
Han Ku Nam +7 more
wiley +1 more source
Animal models of cisplatin‐induced neuropathic pain
Animal Models and Experimental Medicine, EarlyView.This article illustrates the modeling process of a cisplatin‐induced neuropathic pain model in rats or mice. Multiple modeling tests are required for rats or mice before, during, and after modeling. The appropriate injection method, dose, and modeling method are selected, and multiple assays are chosen for evaluation and comparison.
Ningxin Li +9 more
wiley +1 more source
Therapeutic hypothermia after out-of-hospital cardiac arrest in children.
New England Journal of Medicine, 2015 BACKGROUND Therapeutic hypothermia is recommended for comatose adults after witnessed out-of-hospital cardiac arrest, but data about this intervention in children are limited. METHODS We conducted this trial of two targeted temperature interventions at
F. Moler +44 more
semanticscholar +1 more source