Results 111 to 120 of about 16,679,614 (365)
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Application of statistical contrasts to mean refractive state
African Vision and Eye Health, 2006 Testing for differences between specific groups or combinations of groups is referred to as comparison or contrast testing. Statistical significance of comparisons can be assessed by first forming contrasts and then testing for their ...
S Abelman
doaj +1 more source
Dose-response problem in testing the ventricular hypothesis: II. Reply to Khavari, Heebink, and Traupman [PDF]
, 1968 Aryeh Routtenberg
openalex +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Statistics in physical science. Estimation, hypothesis testing and least-squaresby W. C. Hamilton [PDF]
, 1965 A. J. C. Wilson
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Empirical Likelihood based on Hypothesis Testing [PDF]
AMS classifications: 62G10; 62G20; 62G30;estimation;testing ...
Einmahl, J.H.J., McKeague, I.W.
core +1 more source
Using Bayes factor hypothesis testing in neuroscience to establish evidence of absence
Nature Neuroscience, 2020 C. Keysers, V. Gazzola, E. Wagenmakers
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Online multiple hypothesis testing. [PDF]
Stat Sci, 2023 Robertson DS, Wason JMS, Ramdas A.
europepmc +1 more source