Results 111 to 120 of about 4,789,647 (304)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Testing the expectations hypothesis: some new evidence for Japan [PDF]

The deregulation of the Japanese financial markets and the adoption of an interest rate policy instrument by the Bank of Japan prompted a number of empirical investigations of the expectation hypothesis (EH) of the term structures of interest rates in ...
Daniel L. Thornton
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Exports-led growth hypothesis in Pakistan: further evidence [PDF]

The study considers the exports-led growth hypothesis using quarterly data over the period 1990-2008 in case of Pakistan. For this purpose, Ng-Perron unit root test, ARDL bounds testing approach to cointegration and error correction method (ECM) for ...
Ahmad, Khalil, Muhammad, Shahbaz, Pervaz, Azeem   +2 more
core  

hypothesis-testy (data_test_15_02_2017) (1).xlsx

, 2017
Testing the functionality and stability of the software ...
Čeněk Šašinka (3796567)
core   +1 more source

Accountability, fairness, and quality in testing

, 1980
En tête du titre: A Message from Educational Testing ...
Educational Testing Service
core   +1 more source

Large Deviation Analysis of Score-Based Hypothesis Testing

IEEE Access
Score-based statistical models play an important role in modern machine learning, statistics, and signal processing. For hypothesis testing, a score-based hypothesis test is proposed in Wu et al., (2022).
Enmao Diao, Taposh Banerjee, Vahid Tarokh   +2 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Testing Permanent Income Hypothesis for Fiji [PDF]

Hall $(1978)$ has stimulated considerable controversy and empirical work on testing the validity of the permanent income hypothesis $(PIH)$. Much of this work is on the developed countries. In the developing countries incomes show larger fluctuations and
B Bhaskara Rao
core  

Commentary: Psychological Science's Aversion to the Null

Frontiers in Psychology, 2017
Jose D. Perezgonzalez, Dolores Frías-Navarro, Juan Pascual-Llobell   +2 more
doaj   +1 more source