Results 231 to 240 of about 16,679,614 (365)
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo+11 more
wiley +1 more source
A randomisation test of the null hypothesis that two cladograms are sample estimates of a parametric phylogenetic tree [PDF]
Allen G. Rodrigo+3 more
openalex +1 more source
Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno+12 more
wiley +1 more source
Estimating the perceived dimension of psychophysical stimuli using triplet accuracy and hypothesis testing. [PDF]
Künstle DE, von Luxburg U, Wichmann FA.
europepmc +1 more source
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr+5 more
wiley +1 more source
On the Nuisance Parameter Elimination Principle in Hypothesis Testing. [PDF]
Flórez Rivera AF+3 more
europepmc +1 more source
Correction: MultipleTesting.com: A tool for life science researchers for multiple hypothesis testing correction. [PDF]
Menyhart O, Weltz B, Győrffy B.
europepmc +1 more source
The empirical characteristic function and large sample hypothesis testing
John Kellermeier
openalex +1 more source
R2: A computer program for interval estimation, power Calculations, sample size estimation, and hypothesis testing in multiple regression [PDF]
James H. Steiger, Rachel T. Fouladi
openalex +1 more source
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley +1 more source