Results 41 to 50 of about 997,357 (330)
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra+7 more
wiley +1 more source
Hypothesis testing and statistical analysis of microbiome
After the initiation of Human Microbiome Project in 2008, various biostatistic and bioinformatic tools for data analysis and computational methods have been developed and applied to microbiome studies.
Yinglin Xia, Jun Sun
doaj +1 more source
Minimum Probability of Error of List M-ary Hypothesis Testing [PDF]
We study a variation of Bayesian M-ary hypothesis testing in which the test outputs a list of L candidates out of the M possible upon processing the observation. We study the minimum error probability of list hypothesis testing, where an error is defined as the event where the true hypothesis is not in the list output by the test.
arxiv
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet+4 more
wiley +1 more source
Optimal tests of the composite null hypothesis arising in mediation analysis [PDF]
The indirect effect of an exposure on an outcome through an intermediate variable can be identified by a product of regression coefficients under certain causal and regression modeling assumptions. In this context, the null hypothesis of no indirect effect is a composite null hypothesis, as the null holds if either regression coefficient is zero.
arxiv
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Probability, clinical decision making and hypothesis testing
Few clinicians grasp the true concept of probability expressed in the ′P value.′ For most, a statistically significant P value is the end of the search for truth. In fact, the opposite is the case.
A Banerjee, S L Jadhav, J S Bhawalkar
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
The assessment centre: testing the fairness hypothesis
Accumulated international research reveals that assessment centre technology appears to be reasonably 'fair' based on race, sex, and age. Similar research on the assessment centre in South Africa is mostly unknown and/or un-documented. The sample of this
D. N. Hurst, J. A. E. Charoux
doaj +1 more source
Chi-squared test for hypothesis testing of homogeneity [PDF]
We provide necessary and sufficient conditions of uniform consistency of nonparametric sets of alternatives of chi-squared test for testing of hypothesis of homogeneity. The number of cells of chi-squared test increases with sample size growth. Nonparametric sets of alternatives can be defined both in terms of densities and distribution functions.
arxiv