Results 51 to 60 of about 997,357 (330)
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
Replication of null results: Absence of evidence or evidence of absence?
eLifeIn several large-scale replication projects, statistically non-significant results in both the original and the replication study have been interpreted as a ‘replication success.’ Here, we discuss the logical problems with this approach: Non-significance
Samuel Pawel +3 more
doaj +1 more source
Some hypothesis testing problems for categorical variables
Statistica, 2007 This paper considers some testing problems for multivariate categorical variables within a conditional, or permutation, framework. The key idea is based on the decomposition of null and alternative hypotheses into a number of sub-hypotheses. For each sub-
Fortunato Pesarin
doaj +1 more source
Privacy-Utility Management of Hypothesis Tests [PDF]
arXiv, 2018 The trade-off of hypothesis tests on the correlated privacy hypothesis and utility hypothesis is studied. The error exponent of the Bayesian composite hypothesis test on the privacy or utility hypothesis can be characterized by the corresponding minimal Chernoff information rate.
arxiv
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Reliability of Sequential Hypothesis Testing Can Be Achieved by an Almost-Fixed-Length Test [PDF]
arXiv, 2016 The maximum type-I and type-II error exponents associated with the newly introduced almost-fixed-length hypothesis testing is characterized. In this class of tests, the decision-maker declares the true hypothesis almost always after collecting a fixed number of samples $n$; however in very rare cases with exponentially small probability the decision ...
arxiv
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Hypothesis Testing in Weighted Distributions
Journal of Mathematical Extension, 2008 There are many situations in which experiments are not available or data are recorded from the population proportion to a nonnegative function called weight function. In a such situations the classical methods for inferencing about unknown parameters
S. M. R. Alavi, R. Chinipardaz and A. R. Rasekh
doaj
Interpretable hypothesis tests [PDF]
arXiv, 2019 Although hypothesis tests play a prominent role in Science, their interpretation can be challenging. Three issues are (i) the difficulty in making an assertive decision based on the output of an hypothesis test, (ii) the logical contradictions that occur in multiple hypothesis testing, and (iii) the possible lack of practical importance when rejecting ...
arxiv
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source