Results 71 to 80 of about 2,690,705 (301)
Journal of the Royal Statistical Society Series B: Statistical Methodology, 1984 SUMMARY The concept of multiple comparisons between a set of competing hypotheses is examined. A statistic is developed for testing a maintained hypothesis against a series of separate alternatives. This statistic is an extension of the binary Cox test.
openaire +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
HYPOTHESIS TESTING ON STRUCTURAL COMPARATIVE CALIBRATION MODEL
Pesquimat, 2014 .- In this work study statistic inference on comparative calibration model introduced for Barnett [1]. Consider hypothesis testing in structural comparative calibration model presented in Theobald and Mallison [4].
Oiga Lidia Solano Dávíla
doaj +1 more source
Testing Composite Null Hypothesis Based on $S$-Divergences
, 2015 We present a robust test for composite null hypothesis based on the general $S$-divergence family. This requires a non-trivial extension of the results of Ghosh et al.~(2015).
Basu, Ayanendranath, Ghosh, Abhik
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Testing the Resource Hypothesis of Species–Area Relationships: Extinction Cannot Work Alone [PDF]
, 2022 Wei Deng +5 more
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Recent developments towards optimality in multiple hypothesis testing
, 2006 There are many different notions of optimality even in testing a single hypothesis. In the multiple testing area, the number of possibilities is very much greater.
Shaffer, Juliet Popper
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Hypothesis testing for Gaussian states on bosonic lattices
, 2008 The asymptotic state discrimination problem with simple hypotheses is considered for a cubic lattice of bosons. A complete solution is provided for the problems of the Chernoff and the Hoeffding bounds and Stein's lemma in the case when both hypotheses ...
Davies E. B. +5 more
core +3 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source