Novel associations for hypothyroidism include known autoimmune risk loci [PDF]
, 2011 Hypothyroidism is the most common thyroid disorder, affecting about 5% of the general population. Here we present the first large genome-wide association study of hypothyroidism, in 2,564 cases and 24,448 controls from the customer base of 23andMe, Inc.,
A Alcina +57 more
core +18 more sources
Relation of kidney function and homocysteine in patients with hypothyroidism
Endocrine Connections, 2021 Objective: It has been found that both serum homocysteine (Hcy) and serum creatinine levels were increased in hypothyroidism patients. The aim of this study was to investigate the correlation between serum Hcy and kidney function in patients with ...
Qingrong Pan +8 more
doaj +1 more source
NEWBORN SCREENING FOR PHENYLKETONURIA AND CONGENITAL HYPOTHYROIDISM: RESULTS FROM CLUJ CENTER, 2011-2015 [PDF]
Romanian Journal of Pediatrics, 2017 Objectives. The aim of our study was to assess the current state of newborn screening (NBS) for two innate errors of metabolism, phenylketonuria (PKU) and congenital hypothyrodism (CH) in the north-west part of Romania, in Cluj regional center (CJRC ...
Carmen Costache +2 more
doaj +1 more source
Primary hypothyroidism as a predictor of the hypogonadism development
Mìžnarodnij Endokrinologìčnij Žurnal, 2021 Background. Human lifestyle significantly affects human health and reproductive functions. The presence of hypothyroidism negatively impacts the health, activity, and reproductive status.
N.V. Pasyechko +4 more
doaj +1 more source
Systemic Lupus Erythematosus Patients With Related Organic Damage Are at High Risk of Hypothyroidism
Frontiers in Endocrinology, 2022 PurposeThe aim of this study included determining the prevalence of hypothyroidism in patients with systemic lupus erythematosus (SLE), clarifying the clinical characteristics of SLE patients with hypothyroidism, and identifying the relationship between ...
Jiajia Ni +6 more
doaj +1 more source
Metabolic profiling provides a system understanding of hypothyroidism in rats and its application. [PDF]
PLoS ONE, 2013 BACKGROUND: Hypothyroidism is a chronic condition of endocrine disorder and its precise molecular mechanism remains obscure. In spite of certain efficacy of thyroid hormone replacement therapy in treating hypothyroidism, it often results in other side ...
Si Wu +6 more
doaj +1 more source
Laboratory indicators of hypothyroidism and TgAA-positivity in the Eurasian dog breed
PLoS ONE, 2023 Background Hereditary hypothyroidism represents a concern for dog breeders; thus, surveillance programs have been established for several dog breeds. Methods Thyroid profiles (total thyroxine (TT4), thyrotropin (thyroid stimulating hormone (TSH)), and ...
Martina Schlipf +8 more
doaj +2 more sources
Lipid peroxidation in the serum of hypothyroid patients (In Gorgan-South East of Caspian Sea) [PDF]
, 2008 This study was designed to determine if lipid peroxidation can be modified by hypothyroidism. Twenty eight subjects with hypothyroidism and 33 euthyroid subjects participated in this study (2007).
Ahmadi, A. +4 more
core +1 more source
Massive pericardial effusion caused by hypothyroidism. [PDF]
, 2018 Although mild pericardial effusion is a usual finding in patients with hypothyroidism, massive pericardial effusion or pericardial tamponade is rare and customarily related to severe hypothyroidism. The diagnosis of hypothyroidism should be considered in
Germano, A, Roque, D, Schmitt, W
core +1 more source
Frontiers in Endocrinology, 2020 Background: Hypothyroidism is known to be correlated with multiple heart diseases. However, the influence of hypothyroidism on the patients with heart valve disease (HVD) is still unclear.
Tianyu Zhai +3 more
doaj +1 more source