Results 31 to 40 of about 214,172 (303)

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

open access: yesHepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou   +13 more
wiley   +1 more source

Hypothyroidism in Pregnancy [PDF]

open access: yesEndocrinology and Metabolism Clinics of North America, 2019
Thyroid hormone is essential for pregnancy and ensuring fetal development. Pregnancy also places substantial demands on the thyroid axis. Overt hypothyroidism is associated with substantial adverse obstetric and offspring outcomes and requires treatment.
Taylor, Peter N., Lazarus, John H.
openaire   +2 more sources

Hypothyroidism: current state of the problem

open access: yesМедицинский совет, 2020
The article presents the issues of epidemiology, classification, and clinic of hypothyroidism. The frequency of hypothyroidism increases significantly with age.
E. V. Biryukova   +2 more
doaj   +1 more source

Genetic association and Mendelian randomization for hypothyroidism highlight immune molecular mechanisms

open access: yesiScience, 2022
Summary: We carried out a genome-wide association analysis including 51,194 cases of hypothyroidism and 443,383 controls. In total, 139 risk loci were associated to hypothyroidism with genes involved in lymphocyte function.
Samuel Mathieu   +9 more
doaj   +1 more source

Treatment of Subclinical Hypothyroidism or Hypothyroxinemia in Pregnancy

open access: yesNew England Journal of Medicine, 2017
Background Subclinical thyroid disease during pregnancy may be associated with adverse outcomes, including a lower‐than‐normal IQ in offspring. It is unknown whether levothyroxine treatment of women who are identified as having subclinical hypothyroidism
B. Casey   +17 more
semanticscholar   +1 more source

Risk Factors for Clinically Overt Hypothyroidism in Unselected Population of Adult Epilepsy Patients

open access: yesArchives of Epilepsy, 2023
Objective:This study aimed to investigate the risk factors for hypothyroidism in patients with adult epilepsy patients.Methods:Hospital charts of 530 patients were reviewed retrospectively.
Naciye Çilem Çarkı Bal   +2 more
doaj   +1 more source

Hypothyroidism in Elderly Population: A Review

open access: yesJournal of Clinical and Basic Research, 2017
Many metabolic disorders originate from thyroid disorders, particularly from hypothyroidism. Hypothyroidism commonly occurs in elderly subjects, particularly in women. Subclinical form of hypothyroidism can be diagnosed via laboratory testing.
Akhtar Saifi   +2 more
doaj   +2 more sources

To Treat or Not to Treat Subclinical Hypothyroidism, What Is the Evidence?

open access: yesMedicina, 2020
Objective: levothyroxine prescriptions have increased remarkably during the last decade, and it is most likely to be prescribed in subclinical hypothyroidism. The aim of this review was to present data on when levothyroxine treatment should be initiated,
J. Calissendorff, H. Falhammar
semanticscholar   +1 more source

Role of hypothyroidism and associated pathways in pregnancy and infertility: Clinical insights

open access: yesTzu-Chi Medical Journal, 2020
Thyroid disorders are the most common endocrine problems in women. In most of the cases, thyroid can lead to infertility or miscarriages. The etiology of infertility is multifactorial with thyroid disorders as the most common presenting factor ...
Arun Koyyada, Prabhakar Orsu
semanticscholar   +1 more source

Hypothyroidism in vasculitis

open access: yesRheumatology, 2021
Abstract Objective To study the prevalence, risk and clinical associations of hypothyroidism among several forms of vasculitis. Methods Patients with GCA, Takayasu’s arteritis (TAK), PAN and the three forms of ANCA-associated ...
Tanaz A Kermani   +14 more
openaire   +4 more sources

Home - About - Disclaimer - Privacy