Results 31 to 40 of about 164,493 (304)
iScience, 2022 Summary: We carried out a genome-wide association analysis including 51,194 cases of hypothyroidism and 443,383 controls. In total, 139 risk loci were associated to hypothyroidism with genes involved in lymphocyte function.
Samuel Mathieu +9 more
doaj +1 more source
Hypothyroidism: current state of the problem
Медицинский совет, 2020 The article presents the issues of epidemiology, classification, and clinic of hypothyroidism. The frequency of hypothyroidism increases significantly with age.
E. V. Biryukova +2 more
doaj +1 more source
Study on metabolic status of tear fluid in hypothyroidism patients with dry eye syndrome
Journal of Ophthalmology, 2018 Introduction. Dry eye syndrome (DES) is associated with a complicated multifactorial mechanism, the peculiarities of which are being studied at the moment.
M.I. Pavlovskii , G.I. Drozhzhyna
doaj +1 more source
Hypothyroidism in Pregnancy [PDF]
Endocrinology and Metabolism Clinics of North America, 2019 Thyroid hormone is essential for pregnancy and ensuring fetal development. Pregnancy also places substantial demands on the thyroid axis. Overt hypothyroidism is associated with substantial adverse obstetric and offspring outcomes and requires treatment.
Taylor, Peter N., Lazarus, John H.
openaire +2 more sources
Hepatology, EarlyView., 2022 Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou +13 more
wiley +1 more source
Frontiers in Endocrinology, 2017 BackgroundPrevious studies propose that hypothyroidism might play a crucial role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD), but findings from published studies on the relationship between hypothyroidism and NAFLD are still ...
Weiwei He +6 more
doaj +1 more source
Rheumatology, 2021 Abstract Objective To study the prevalence, risk and clinical associations of hypothyroidism among several forms of vasculitis. Methods Patients with GCA, Takayasu’s arteritis (TAK), PAN and the three forms of ANCA-associated ...
Tanaz A Kermani +14 more
openaire +4 more sources
Hypothyroidism in Elderly Population: A Review
Journal of Clinical and Basic Research, 2017 Many metabolic disorders originate from thyroid disorders, particularly from hypothyroidism. Hypothyroidism commonly occurs in elderly subjects, particularly in women. Subclinical form of hypothyroidism can be diagnosed via laboratory testing.
Akhtar Saifi +2 more
doaj +2 more sources
Rising Incidence and Comorbidities of Endogenous Hypothyroidism in Republic of Korea from 2004 to 2018: A Nationwide Population Study [PDF]
Endocrinology and MetabolismBackground Hypothyroidism, a prevalent endocrine disorder, results from insufficient thyroid hormone production or release, affecting metabolism. However, disparities in comorbidities and treatment trajectories may exist between endogenous and exogenous ...
Chae Won Chung +3 more
doaj +1 more source
Novel associations for hypothyroidism include known autoimmune risk loci [PDF]
, 2011 Hypothyroidism is the most common thyroid disorder, affecting about 5% of the general population. Here we present the first large genome-wide association study of hypothyroidism, in 2,564 cases and 24,448 controls from the customer base of 23andMe, Inc.,
Amy K. Kiefer (160836) +25 more
core +1 more source