Results 91 to 100 of about 214,172 (303)

Randomized Phase II Trial of Consolidation Pembrolizumab After Definitive Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma: KCSG HN19‐09, CONPELAN Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The benefit of consolidation programmed cell death protein 1 (PD‐1) blockade after chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. Methods Patients with stages II–IVB NPC were randomized (2:1) to pembrolizumab 200 mg or placebo every 3 weeks for up to 17 cycles after chemoradiotherapy ...
Sang Hoon Chun   +11 more
wiley   +1 more source

What is the association of hypothyroidism with risks of cardiovascular events and mortality? A meta-analysis of 55 cohort studies involving 1,898,314 participants

open access: yesBMC Medicine, 2017
BackgroundWhether hypothyroidism is an independent risk factor for cardiovascular events is still disputed. We aimed to assess the association between hypothyroidism and risks of cardiovascular events and mortality.MethodsWe searched PubMed and Embase ...
Y. Ning   +15 more
semanticscholar   +1 more source

Subclinical hypothyroidism unmasked by preeclampsia and ascites

open access: yesIndian Journal of Endocrinology and Metabolism, 2013
Subclinical hypothyroidism is an asymptomatic endocrine disorder while hypothyroidism, on the other hand, can present with a wide range of clinical features which may be nonspecific.
A Ipadeola, G C Nkwocha, J O Adeleye
doaj   +1 more source

Clinical, Radiologic and Cytologic Predictors of Malignancy in Pediatric Thyroid Nodules: Insights From a 26‐Year Cohort Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Introduction Thyroid nodules are less common but more often malignant in pediatric patients than in adults. Our objectives were to study the features of benign vs. malignant thyroid nodules in a large pediatric patient cohort. Methods Retrospective observational cohort study. Consecutive patients aged 0.01–17.9 years at evaluation between 1997–
Maxime Gest‐Laurent   +15 more
wiley   +1 more source

Features of diagnosis and treatment of central hypothyroidism

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2019
Review of literature is devoted to central (se­condary) hypothyroidism, a rare disease. There is a number of questions and difficulties in diagnosis and management of this condition.
V.A. Maslyanko
doaj   +1 more source

Maternal Thyroid Diseases, Medication Use and Childhood Cancer Risks in Offspring: A Population‐Based Cohort Study in Denmark

open access: yesInternational Journal of Cancer, EarlyView.
Thyroid diseases are common among women of reproductive age and may be related to childhood cancer, but the evidence is inconsistent. This study of childhood cancer with maternal thyroid diseases and medication use in a population‐based case‐control study using Danish registries found positive associations between maternal goiter and overall cancer ...
Chuanjie Deng   +5 more
wiley   +1 more source

Role of irisin in Chinese patients with hypothyroidism: an interventional study

open access: yesJournal of International Medical Research, 2019
Objective Irisin is a myokine that greatly affects energy expenditure and systemic metabolism. While thyroid hormone is likely associated with irisin, a direct relationship remains to be fully elucidated.
Ning Yang   +6 more
doaj   +1 more source

Metabolic and hemostatic parameters in patients with type 2 diabetes and hypothyroidism

open access: yesКлиническая и экспериментальная тиреоидология, 2011
To identify hemostatic and metabolic abnormalities in patients with hypothyroidism of varying severity and duration and possible modifying effects of chronic hyperglycemia on the investigated parameters comprehensive analysis of the parameters of ...

doaj   +1 more source

Maternal and neonatal outcomes in Gaza amid armed hostilities in 2025

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study documents facility‐based maternal, obstetric, and neonatal outcomes and associated conflict‐related exposures and living conditions among pregnancy‐related encounters at Al‐Helou Maternity Hospital in Gaza from late April to early September 2025, with a small number of additional encounters recorded at Al‐Shifa Medical ...
Shaymaa Abuhaiba   +16 more
wiley   +1 more source

Congenital hypothyroidism: insights into pathogenesis and treatment

open access: yesInternational Journal of Pediatric Endocrinology, 2017
Congenital hypothyroidism occurs in approximately 1 in 2000 newborns and can have devastating neurodevelopmental consequences if not detected and treated promptly.
Christine E. Cherella, Ari J. Wassner
semanticscholar   +1 more source

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