Results 241 to 250 of about 226,707 (335)

Is it time to offer routine screening for iron deficiency in healthy adolescent females?

British Journal of Haematology, EarlyView.
Given the high prevalence of iron deficiency (ID) in adolescents and the significant health consequences it entails, we recommend screening all female adolescents for ID using serum haemoglobin and ferritin, starting at age 14–15 (approximately 3 years post‐menarche) and repeating every 5 years.
Shoshana Revel‐Vilk, Tal Ben‐Ami, Naama Constantini   +2 more
wiley   +1 more source

Subtype-specific causal effects of hypothyroidism on obstructive sleep apnea: A bidirectional Mendelian randomization study. [PDF]

Medicine (Baltimore)
Zhang H, Wu Z, Chen Q, Yu G, Chen L, Ma Y, Chen Y.   +6 more
europepmc   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Impending myxedema as a manifestation of subclinical hypothyroidism in a case of systemic lupus erythematosus: A case report. [PDF]

Medicine (Baltimore)
Gebremichael EH, Woyimo TG.
europepmc   +1 more source

KEYNOTE‐A17: First‐Line Pembrolizumab Plus Cisplatin–Pemetrexed in Japanese Participants With Advanced Pleural Mesothelioma

Cancer Science, EarlyView.
In the phase 1b KEYNOTE‐A17 study of first‐line pembrolizumab plus chemotherapy in Japanese participants with advanced pleural mesothelioma (PM), 2 of 18 participants (11%) evaluated experienced dose‐limiting toxicities. The objective response rate among all 19 participants in the study was 74%, with 14 participants achieving a partial response and a ...
Takashi Kijima, Terufumi Kato, Yasushi Goto, Kozo Kuribayashi, Koji Mikami, Yoshiki Negi, Shuji Murakami, Tatsuya Yoshida, Masae Homma, Akira Wakana, Kazuo Noguchi, Nobukazu Fujimoto   +11 more
wiley   +1 more source

Prevalence and Risk Factors of Subclinical and Overt Hypothyroidism in Saudi Arabia: A Systematic Review. [PDF]

Cureus
Alhajri AHM, Saleh Al Saad AMS, Idrees H, Hamednalla Mohamed OM, Mohammednoor M, Ibrahim Ahmed IO, Dawod Faky FS.   +6 more
europepmc   +1 more source

ONO‐4578 Plus Nivolumab in Unresectable Advanced or Recurrent Gastric or Gastroesophageal Junction Cancer

Cancer Science, EarlyView.
The limited efficacy of current immune checkpoint inhibitors requires new approaches to overcome immunosuppression. In this phase 1 study, ONO‐4578 plus nivolumab showed a manageable safety profile, signs of antitumor activity, and immune activation, providing reference for further studies evaluating the clinical benefit of ONO‐4578 and nivolumab in ...
Akihito Kawazoe, Kensei Yamaguchi, Tetsuya Hamaguchi, Yukiya Narita, Shogen Boku, Takashi Oshima, Hiroki Hara, Yasuo Hamamoto, Kenji Ishido, Taito Esaki, Hisashi Hosaka, Hirofumi Yasui, Keisuke Koeda, Tomohiro Nishina, Yasushi Tsuji, Takeo Fukagawa, Masahiro Goto, Eiji Oki, Naotoshi Sugimoto, Hiroshi Matsuoka, Fumiharu Yokoyama, Tomoko Yoshida, Kazuo Yoshida, Yoshiaki Oshima, Satoru Iwasa   +24 more
wiley   +1 more source

Porcine Fetal Hypothyroidism Induces Temporal and Tissue-Specific Alterations in the Insulin-Like Growth Factor System. [PDF]

Compr Physiol
Smith AA, Pasternak JA.
europepmc   +1 more source

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

Clinical Endocrinology, EarlyView.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan, James M. Hawley, Leanne Cussen, Ali Abbara, Sophie A. Clarke, Punith Kempegowda, Rima K. Dhillon‐Smith, Puja Thadani, Maureen Busby, Lucy Owusu‐Darkwah, Rachel Marrington, W. Colin Duncan, Robert K. Semple, Richard Quinton, Michael W. O'Reilly   +14 more
wiley   +1 more source

Reconsidering the timing of levothyroxine discontinuation in children with congenital hypothyroidism: insights from a Korean Cohort Study - commentary on "Predicting variables associated with diagnostic reevaluation of transient congenital hypothyroidism". [PDF]

Ann Pediatr Endocrinol Metab
Jeong HR.
europepmc   +1 more source