Results 41 to 50 of about 318,820 (346)
iScience, 2022 Summary: We carried out a genome-wide association analysis including 51,194 cases of hypothyroidism and 443,383 controls. In total, 139 risk loci were associated to hypothyroidism with genes involved in lymphocyte function.
Samuel Mathieu +9 more
doaj +1 more source
A hidden cause of infertility in hypothyroid patients [PDF]
, 2020 Methylene tetrahydrofolate reductase (MTHFR) gene mutations could be the cause of infertility in hypothyroid patients. Hence, it is worthy to screen for MTHFR gene mutations in infertile hypothyroid females and their partners if infertility persists ...
Ahmed, Soha Magdy +4 more
core +1 more source
Hypothyroidism: current state of the problem
Медицинский совет, 2020 The article presents the issues of epidemiology, classification, and clinic of hypothyroidism. The frequency of hypothyroidism increases significantly with age.
E. V. Biryukova +2 more
doaj +1 more source
Maternal thyroid function and child educational attainment: prospective cohort study [PDF]
, 2018 Objective: To determine if first trimester maternal thyroid dysfunction is a critical determinant of child scholastic performance and overall educational attainment. Design: Prospective cohort study.
Haig, Caroline +7 more
core +3 more sources
Journal of the American Medical Association (JAMA), 2018 Importance The benefit of thyroid hormone therapy for subclinical hypothyroidism is uncertain. New evidence from recent large randomized clinical trials warrants an update of previous meta-analyses. Objective To conduct a meta-analysis of the association
M. Feller +14 more
semanticscholar +1 more source
Diagnosis and management of treatment-refractory hypothyroidism: an expert consensus report [PDF]
, 2017 There is a frequently encountered subset of hypothyroid patients who are refractory to standard thyroid hormone replacement treatment and require unexpectedly high doses of levothyroxine.
Benvenga, S +2 more
core +1 more source
Role of hypothyroidism and associated pathways in pregnancy and infertility: Clinical insights
Tzu-Chi Medical Journal, 2020 Thyroid disorders are the most common endocrine problems in women. In most of the cases, thyroid can lead to infertility or miscarriages. The etiology of infertility is multifactorial with thyroid disorders as the most common presenting factor ...
Arun Koyyada, Prabhakar Orsu
semanticscholar +1 more source
To Treat or Not to Treat Subclinical Hypothyroidism, What Is the Evidence?
Medicina, 2020 Objective: levothyroxine prescriptions have increased remarkably during the last decade, and it is most likely to be prescribed in subclinical hypothyroidism. The aim of this review was to present data on when levothyroxine treatment should be initiated,
J. Calissendorff, H. Falhammar
semanticscholar +1 more source
Hypothyroidism in Elderly Population: A Review
Journal of Clinical and Basic Research, 2017 Many metabolic disorders originate from thyroid disorders, particularly from hypothyroidism. Hypothyroidism commonly occurs in elderly subjects, particularly in women. Subclinical form of hypothyroidism can be diagnosed via laboratory testing.
Akhtar Saifi +2 more
doaj +2 more sources
Thyroxine treatment in patients with symptoms of hypothyroidism but thyroid function tests within the reference range: randomised double blind placebo controlled crossover trial [PDF]
, 2001 OBJECTIVES: To determine whether thyroxine treatment is effective in patients with symptoms of hypothyroidism but with thyroid function tests within the reference range, and to investigate the effect of thyroxine treatment on psychological and physical ...
Davidson, K.M. +6 more
core +2 more sources