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Copeptin in the differential diagnosis of hypotonic polyuria

Journal of Endocrinological Investigation, 2019
Copeptin is secreted in equimolar amount to Arginine Vasopressin (AVP) but can easily be measured with a sandwich immunoassay. Both peptides, copeptin and AVP, show a high correlation. Accordingly, copeptin mirrors the amount of AVP in the circulation and its measurement provides an attractive marker in the differential diagnosis of diabetes insipidus ...
Mirjam Christ-Crain
exaly   +5 more sources

Marked Hypotonic Polyuria Resulting from Nephrogenic Diabetes Insipidus with Partial Sensitivity to Vasopressin*

Journal of Clinical Endocrinology and Metabolism, 1984
We studied two women with severe hypotonic polyuria whose symptoms dated from infancy. We eliminated the possibility of central diabetes insipidus (DI) and primary polydipsia, and established the presence of nephrogenic DI on the basis of: 1) the interrelationships between plasma osmolality, urine osmolality, and urinary AVP; and 2) impaired ...
Arnold M Moses   +2 more
exaly   +3 more sources

Effects of experimental potassium depletion on renal function and urinary prostanoid excretion in normal women during hypotonic polyuria

Clinical Physiology, 1990
Summary. During hypotonic polyuria renal function studies by the clearance (cl.) method, and urinary PGE2, 6‐keto‐PGF1α and TxB2 determinations were performed on 14 healthy women in normal potassium balance (N) and 14 healthy women in sustained potassium depletion (KD) induced by low dietary potassium intake (≤ 10 mmol day‐1) and natriuretic treatment.
G C, Agnoli   +6 more
exaly   +3 more sources

Juvenile Nephronophthisis. Part I A Genetically Determined Nephropathy with Hypotonic Polyuria and Azotaemia

Acta Paediatrica, International Journal of Paediatrics, 1960
O. BROBERGER   +2 more
exaly   +2 more sources

Hypotonic polyuria: at the cross-roads of copeptin.

The Netherlands journal of medicine, 2021
The aetiology of hypotonic polyuria, after excluding solute diuresis, is one of primary polydipsia, central, or nephrogenic diabetes insipidus. Theoretically, these disorders should be relatively easily distinguished based on history and the results of an indirect water deprivation test.
A, Gupta, D, Zimmerman
openaire   +1 more source

Hypotonic polyuria syndrome after electrical burns: a case reports study

Neurologia Croatica. Supplement, 2007
Aim. Electrical fields damage the cells by thermal and non-thermal mechanisms. It causes cells lysis, disturbs electrochemical equilibrium inside and outside the cells and cause cytokines freed from the damaged cells. Giant, muscle and nerve cells are more sensitive to lysis and the most signs of electrical damage are related to neuromuscular injury ...
Bartolek, Dubravka   +3 more
openaire   +3 more sources

[Relation between acute changes in diuresis and renal prostaglandins. I: Induced hypotonic polyuria].

Bollettino della Societa italiana di biologia sperimentale, 1984
We have evaluated the effects of indomethacin (I) and of a rich in linoleic acid phosphatidylcholine (E) on the renal function and on the PGE urinary excretion during steady hypotonic polyuria. 5 normal subjects have been studied in the absence of treatment (TA) and after treatment with I, E, E + I.
Agnoli GC   +4 more
openaire   +2 more sources

[Renal function in experimental potassium depletion. I. Effects of lysine-8-vasopressin in hypotonic polyuria].

Bollettino della Societa italiana di biologia sperimentale, 1990
Renal function has been studied by the clearance (cl.) method during hypotonic polyuria--four 15-min cl. periods--and successive antidiuresis--two 60-min cl. periods (A1, A2)--induced by lysine-8-vasopressin (LVP), 5 mU in bolus followed by infusion at a rate of 0.04 mU/min. The endogenous creatinine cl. (Cc) and the osmotic cls.
G C, Agnoli   +6 more
openaire   +1 more source

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