Results 151 to 160 of about 1,864 (192)
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Hypouricemia Related to a Hypersecretional Tubulopathy
Nephron, 2008We present 1 patient with hypouricemia and hyperuricosuria. Serum uric acid level ranged between 1.5 and 1.9 mg/dl and uric acid fractional excretion between 20 and 28%. Apart from that the renal function was normal. The pyrazinamide suppression test gave a normal response showing nearly complete suppression of urate excretion.
Dumont, Isabelle, Decaux, Guy
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Archives of Internal Medicine, 1974
In the course of one year, two patients were encountered with incidental serum uric acid values of 0.2 and 0.3 mg per 100 ml. Hypouricemia may be more prevalent than would be suggested by the small number of previously reported cases. Urinary uric acid determinations provide a simple means of evaluating the causes of hypouricemia in such patients.
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In the course of one year, two patients were encountered with incidental serum uric acid values of 0.2 and 0.3 mg per 100 ml. Hypouricemia may be more prevalent than would be suggested by the small number of previously reported cases. Urinary uric acid determinations provide a simple means of evaluating the causes of hypouricemia in such patients.
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Oncology, 2009
Two cases of hypouricemia in association with malignant diseases are presented. One patient had metastatic breast cancer and the other an undifferentiated retroperitoneal sarcoma of the childhood. Uric acid renal handling was studied with the pyrazinamide and benzbromarone tests. Both patients had reduced postsecretory reabsorption of uric acid.
Manuel Morales, Victor Garcia-Nieto
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Two cases of hypouricemia in association with malignant diseases are presented. One patient had metastatic breast cancer and the other an undifferentiated retroperitoneal sarcoma of the childhood. Uric acid renal handling was studied with the pyrazinamide and benzbromarone tests. Both patients had reduced postsecretory reabsorption of uric acid.
Manuel Morales, Victor Garcia-Nieto
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Cause of Persistent Hypouricemia in Outpatients
Nephron, 2008We measured serum urate in 3,258 Japanese outpatients. Five of them had persistent hypouricemia. Three also had microhematuria. Four of the five patients were proven to have renal uricosuria with hypouricemia, but otherwise normal tubular function. When tested with both pyrazinamide and benzbromarone, 1 patient had a presecretory reabsorption defect, 2
I, Hisatome +7 more
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Drug Safety
Hypouricemia is defined as a serum uric acid concentration of ≤ 2.0 mg/dL or 119 μmol/L. Hypouricemia may occur secondarily to a number of underlying conditions, including severe hepatocellular disease, neoplasia, defective renal tubular reabsorption of uric acid, inherited metabolic defect in purine metabolism, and drugs.
Chaker, Ben Salem +4 more
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Hypouricemia is defined as a serum uric acid concentration of ≤ 2.0 mg/dL or 119 μmol/L. Hypouricemia may occur secondarily to a number of underlying conditions, including severe hepatocellular disease, neoplasia, defective renal tubular reabsorption of uric acid, inherited metabolic defect in purine metabolism, and drugs.
Chaker, Ben Salem +4 more
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Hypouricemia in total parenteral nutrition
The American Journal of Clinical Nutrition, 1980Profound hypouricemia developed in significant number of patients receiving total parenteral nutrition. Nadir serum uric acid (values between 1 and 2.7 mg/100 ml) were noted between the 2nd and 17th day of the course. Return of serum uric acid to pretreatment values was noted within seven days after the termination of total parenteral nutrition.
A, Al-Jurf, E, Steiger
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Hereditary renal hypouricemia in children
The Journal of Pediatrics, 1985The renal handling of urate was investigated in four children with hereditary renal hypouricemia and in their parents. The urate/creatinine clearance ratios in the four patients were 1.02 +/- 0.28, 0.93 +/- 0.11, 1.03 +/- 0.24, and 1.46 +/- 0.26, markedly higher than those in control subjects.
E, Takeda +9 more
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Molecular Genetics and Metabolism, 2006
Hereditary renal hypouricemia (HRH) is an inborn error of renal membrane transport specific for uric acid, resulting in increased renal urate clearance associated with hypouricemia. Apparently in most HRH patients, the disorder is caused by loss of function mutations in the gene SLC22A12 coding for human urate transporter 1 (hURAT1), shown to control ...
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Hereditary renal hypouricemia (HRH) is an inborn error of renal membrane transport specific for uric acid, resulting in increased renal urate clearance associated with hypouricemia. Apparently in most HRH patients, the disorder is caused by loss of function mutations in the gene SLC22A12 coding for human urate transporter 1 (hURAT1), shown to control ...
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Lung carcinoma, hypouricemia and aminoaciduria
The American Journal of Medicine, 1965Abstract Two cases of bronchogenic carcinoma associated with hypouricemia are presented in which renal clearance studies demonstrated that the hypouricemia was associated with an increased renal clearance of uric acid and generalized renal aminoaciduria.
B, WEINSTEIN, F, IRREVERRE, D M, WATKIN
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Archives of Internal Medicine, 1987
• In diabetes, the serum uric acid level is low due to increased urate clearance; however, its mechanism remains unknown. We examined seven maturity-onset diabetic patients with rarely reported hypouricemia due to renal tubular abnormality to better understand the renal handling of urate by the diabetic kidney.
M, Shichiri, H, Iwamoto, T, Shiigai
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• In diabetes, the serum uric acid level is low due to increased urate clearance; however, its mechanism remains unknown. We examined seven maturity-onset diabetic patients with rarely reported hypouricemia due to renal tubular abnormality to better understand the renal handling of urate by the diabetic kidney.
M, Shichiri, H, Iwamoto, T, Shiigai
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