Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells. [PDF]
Beverly H. Koller+8 more
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Human hypoxanthine-guanine phosphoribosyltransferase. Demonstration of structural variants in lymphoblastoid cells derived from patients with a deficiency of the enzyme. [PDF]
James M. Wilson+4 more
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Characterisation of cDNA clones for hypoxanthine–guanine phosphoribosyltransferase from the human malarial parasite,Plasmodium falciparum: comparisons to the mammalian gene and protein [PDF]
Angus King, David W. Melton
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Adoptive T Cell Therapy for Metastatic Colorectal Cancer [PDF]
Colorectal cancer is the second leading cause of cancer-related death in US (1). Most of the mortality reflects local, regional and distant metastatic tumors.
Ebanks, Shauna
core +1 more source
Small colony variant (SCV) is strongly linked to antibiotic resistance and the persistence of osteomyelitis. However, the intrinsic phenotypic instability of SCV has hindered a thorough investigation of its pathogenic mechanisms.
Tingwang Shi+11 more
doaj +1 more source
Genetic basis of hypoxanthine guanine phosphoribosyltransferase deficiency in a patient with the Lesch-Nyhan syndrome (HPRTFlint) [PDF]
Beverly L. Davidson+3 more
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Identification of a single nucleotide change in the hypoxanthine-guanine phosphoribosyltransferase gene (HPRTYale) responsible for Lesch-Nyhan syndrome. [PDF]
Shin Fujimori+3 more
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Human hypoxanthine-guanine phosphoribosyltransferase: a single nucleotide substitution in cDNA clones isolated from a patient with Lesch-Nyhan syndrome (HPRTMidland) [PDF]
Beverly L. Davidson+2 more
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Molecular basis of hypoxanthine-guanine phosphoribosyltransferase deficiency in thirteen Spanish families [PDF]
Rosa J. Torres+7 more
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