Results 121 to 130 of about 34,291 (223)

Crystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferase

, 2002
Crystal structures have been determined for free Escherichia coli hypoxanthine phosphoribosyltransferase (HPRT) (2.9 Angstrom resolution) and for the enzyme in complex with the reaction products, inosine 5'-monophosphate (IMP) and guanosine 5 ...
Vos, S., Luke W. Guddat, De Jersey, J, Guddat, LW, Keough, D. T., Martin, J. L., Dianne T. Keough, Jennifer L. Martin, Vos, S, Guddat, L. W., John de Jersey, Keough, DT, Siska Vos, De Jersey, J., Martin, JL   +14 more
core   +1 more source

Cytotoxicity screen of the acyclic nucleoside phosphonates against bloodstream stage of \kur{Trypanosoma brucei} and validation of their putative target hypoxanthine/xanthine/guanine phosphoribosyltransferase

, 2012
The aim of this study was to test several compounds of acyclic nucleoside phosphonates (ANPs), which are thought to inhibit the purine salvage pathway enzyme hypoxanthine/xanthine/guanine phosphoribosyltransferase (HGXPRT) of the bloodstream stage of ...
MITTERMAYR, Martina
core  

Resensitizing β‐Lactams by Reprogramming Purine Metabolism in Small Colony Variant for Osteomyelitis Treatment

Advanced Science
Small colony variant (SCV) is strongly linked to antibiotic resistance and the persistence of osteomyelitis. However, the intrinsic phenotypic instability of SCV has hindered a thorough investigation of its pathogenic mechanisms.
Tingwang Shi, Qiong Wu, Zesong Ruan, Zhiyuan Luo, Wenbo Wang, Zhao Guo, Yihong Ma, Xin Wang, Guangyu Chu, Han Lin, Min Ge, Yunfeng Chen   +11 more
doaj   +1 more source

Determination of hipoxanthine and hypoxanthine-guanine phosphoribosyltransferase concentrations in venuos blood of 100 and 400 m runners [PDF]

, 2019
Hipoksantin je purinska baza, ki nastane z razgradnjo adenozin trifosfata, iz mišic se izloča v kri. Encim hipoksantin-gvanin-fosforibozil-transferaza, pretvori hipoksantin v inozin monofosfat, iz katerega lahko ponovno nastane adenozin trifosfat. Gre za
Lindič, Mitja
core  

Primer sequence for qRT-PCR.

, 2013
Note. TRAV10, T cell receptor alpha variable 10; IFN-γ, interferon gamma; HPRT1, Hypoxanthine phosphoribosyltransferase 1;TBP, TATA box binding protein.
Chen-Xin Dai (441350), Yong-Sheng Xiao (178415), Jian Zhou (28020), Jia Fan (178422), Yi-Wei Li (441347), Shuang-Jian Qiu (157512), Ming-Yan Cai (441349), Jie Hu (130301), Qiang Gao (130609), Xiang-Nan Xu (441346), Min-Jie Ju (441348)   +10 more
core   +1 more source

Identifying the best reference gene for RT-qPCR analyses of the three-dimensional osteogenic differentiation of human induced pluripotent stem cells

Bone Reports
Reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) is an essential tool for gene expression analysis; choosing appropriate reference genes for normalization is crucial to ensure data reliability.
Masakazu Okamoto, Yusuke Inagaki, Kensuke Okamura, Yoshinobu Uchihara, Kenichiro Saito, Akihito Kawai, Munehiro Ogawa, Akira Kido, Eiichiro Mori, Yasuhito Tanaka   +9 more
doaj   +1 more source

Synthesis of branched 9-[2-(2-phosphonoethoxy)ethyl]purines as a new class of acyclic nucleoside phosphonates which inhibit Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase

, 2009
The malarial parasite Plasmodium falciparum (Pf) lacks the de novo pathway and relies on the salvage enzyme, hypoxanthine–guanine–xanthine phosphoribosyltransferase (HGXPRT), for the synthesis of the 6-oxopurine nucleoside monophosphates.
Hockova, Dana, Masojidkova, Milena, Holy, Antonín, Guddat, Luke W., Keough, Dianne T., de Jersey, John, Dana Hocková, Antonín Holý, Dianne T. Keough, Luke W. Guddat, John de Jersey, Milena Masojídková   +11 more
core   +1 more source

Generation of hypoxanthine phosphoribosyltransferase gene knockout rabbits by homologous recombination and gene trapping through somatic cell nuclear transfer. [PDF]

Sci Rep, 2015
Yin M, Jiang W, Fang Z, Kong P, Xing F, Li Y, Chen X, Li S.   +7 more
europepmc   +1 more source

Hypoxanthine-Guanine Phosphoribosyltransferase [PDF]

, 2020
openaire   +1 more source

The development of hypoxanthine-guanine phosphoribosyltransferase activity in man [PDF]

Biochemical Journal, 1971
A, Adams, J M, Anderson, A D, Nicol, R A, Harkness   +3 more
openaire   +2 more sources