Results 1 to 10 of about 18,240 (107)

L-arginine metabolism inhibits arthritis and inflammatory bone loss. [PDF]

Ann Rheum Dis, 2023
Objectives To investigate the effect of the L-arginine metabolism on arthritis and inflammation-mediated bone loss. Methods L-arginine was applied to three arthritis models (collagen-induced arthritis, serum-induced arthritis and human TNF transgenic ...
Cao S, Li Y, Song R, Meng X, Fuchs M, Liang C, Kachler K, Meng X, Wen J, Schlötzer-Schrehardt U, Taudte V, Gessner A, Kunz M, Schleicher U, Zaiss MM, Kastbom A, Chen X, Schett G, Bozec A.   +18 more
europepmc   +2 more sources

Synthesis and Properties of Isomeric Di- and Mono-Glucopyranosyl Hypoxanthines

Agricultural and Biological Chemistry, 1968
Takeshi Hashizume, Hajime Yamasaki
exaly   +2 more sources

Biosensors in Evaluation of Quality of Meat and Meat Products – A Review

, 2020
Biosensors can find application in meat and meat products testing for safety, including microbial and other contaminants, and quality, including meat freshness, beef tenderness and pork quality defects.
B. Sionek, W. Przybylski, Krzysztof Tambor   +2 more
semanticscholar   +1 more source

Three Hypoxanthine Derivatives from the Marine Cyanobacterium Okeania hirsuta

Molbank
Three novel hypoxanthine derivatives (1–3) were obtained from the Okinawan cyanobacterium Okeania hirsuta. The structures of these compounds were elucidated mainly based on the spectroscopic data, including 1D and 2D NMR, as well as high-resolution mass ...
Ryoya Kawabe, Botao Zhang, Ryuichi Watanabe, Hajime Uchida, Masayuki Satake, Hiroshi Nagai   +5 more
doaj   +1 more source

Xanthine oxidoreductase: One enzyme for multiple physiological tasks

Redox Biology, 2021
Human xanthine oxidoreductase (XOR) is a multiple-level regulated enzyme, resulting from a complicated evolutionary process that assigned it many physiological roles.
M. Bortolotti, L. Polito, M. Battelli, A. Bolognesi   +3 more
semanticscholar   +1 more source

Post-synthetic and site-specific modification of endocyclic nitrogen atoms of purines in DNA and its potential for biological and structural studies

Nucleic Acids Research, 2005
Site-specific modification of the N1-position of purine was explored at the nucleoside and oligomer levels. 2′-Deoxyinosine was converted into an N1-2,4-dinitrophenyl derivative 2 that was readily transformed to the desired N1-substituted 2′-deoxyinosine
R. Narukulla, D. E. Shuker, Yao-Zhong Xu
semanticscholar   +1 more source

Allopurinol and oxypurinol differ in their strength and mechanisms of inhibition of xanthine oxidoreductase

Journal of Biological Chemistry, 2023
Xanthine oxidoreductase is a metalloenzyme that catalyzes the final steps in purine metabolism by converting hypoxanthine to xanthine and then uric acid.
Mai Sekine, Ken Okamoto, E. Pai, K. Nagata, K. Ichida, R. Hille, T. Nishino   +6 more
semanticscholar   +1 more source

Rhizosphere metabolite-mediated soil enhancement: long-term biochar application optimizes continuous soybean production systems

Biochar
Biochar offers promising solutions for agricultural sustainability, yet the intricate mechanisms governing rhizosphere metabolite-microbe-soil interactions remain poorly understood. Through a decade-long field experiment, the effects of sustained biochar
Di Wu, Yuxue Zhang, Wenqi Gu, Zifan Liu, Wenjia Wang, Yuanyuan Sun, Liqun Xiu, Weiming Zhang, Wenfu Chen   +8 more
doaj   +1 more source

Surface-Enhanced Raman Analysis of Uric Acid and Hypoxanthine Analysis in Fractionated Bodily Fluids

Nanomaterials, 2023
In recent years, the disease burden of hyperuricemia has been increasing, especially in high-income countries and the economically developing world with a Western lifestyle. Abnormal levels of uric acid and hypoxanthine are associated with many diseases,
F. Tian, L. F. das Chagas e Silva de Carvalho, A. Casey, M. Nogueira, Hugh J. Byrne   +4 more
semanticscholar   +1 more source

De novo and Salvage Purine Synthesis Pathways Across Tissues and Tumors

Cell
SUMMARY Purine nucleotides are vital for RNA and DNA synthesis, signaling, metabolism, and energy homeostasis. To synthesize purines, cells use two principal routes: the de novo and salvage pathways. Traditionally, it is believed that proliferating cells
Diem H. Tran, Dohun Kim, Rushendhiran Kesavan, Harrison Brown, Trishna Dey, M. H. Soflaee, Hieu S. Vu, Alpaslan Tasdogan, Jason Guo, Divya Bezwada, Houssam Al-Saad, F. Cai, Ashley Solmonson, Halie Rion, Rawand Chabatya, Salma Merchant, N. J. Manales, V. Tcheuyap, Megan Mulkey, Thomas P. Mathews, J. Brugarolas, Sean J. Morrison, Hao Zhu, R. DeBerardinis, Gerta Hoxhaj   +24 more
semanticscholar   +1 more source