Metabolomics in Team-Sport Athletes: Current Knowledge, Challenges, and Future Perspectives. [PDF]
Metabolomics is a promising tool for studying exercise physiology and exercise-associated metabolism. It has recently been defined with the term "sportomics" due to metabolomics' capability to characterize several metabolites in several biological ...
Bongiovanni T +5 more
europepmc +4 more sources
Preliminary study on the potential impact of probiotic combination therapy on Helicobacter pylori infection in children using 16S gene sequencing and untargeted metabolomics approach. [PDF]
ObjectiveThe purpose of this study was to explore the potential mechanism of Helicobacter pylori (Hp) eradication by probiotic therapy through 16S rRNA gene sequencing technology and untargeted metabolomics.MethodsTwenty four Hp-infected children were ...
Yan Y +7 more
europepmc +3 more sources
Sibling species differently distributed around a CO<sub>2</sub> vent show transplantation proteomic remodelling, while displaying metabolomic signatures associated with their origin. [PDF]
The cellular homeostatic response (CHR) and cellular stress response (CSR) work together to maintain homeostasis. Studying phylogenetically closely-related species inhabiting different environments can help investigate the interplay between the CHR and ...
Turner LM +8 more
europepmc +3 more sources
The role of veracity on the load monitoring of professional soccer players: a systematic review in the face of the big data era [PDF]
Big Data has real value when the veracity of the collected data has been previously identified. However, data veracity for load monitoring in professional soccer players has not been analyzed yet.
Afonso, José +11 more
core +2 more sources
Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC [PDF]
Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways.
Alberto Contreras-Sanz +60 more
core +2 more sources
Beneficial Effects of Ketogenic Diet on Phosphofructokinase Deficiency (Glycogen Storage Disease Type VII) [PDF]
Background: A deficiency of muscle phosphofructokinase (PFKM) causes a rare metabolic muscle disease, the Tarui disease (Glycogen storage disease type VII, GSD VII) characterized by exercise intolerance with myalgia due to an inability to use glucose as ...
Auranen, Mari +2 more
core +1 more source
Assessment of free radical scavenging and digestive enzyme inhibitory activities of extract, fractions and isolated compounds from Tetracera macrophylla leaves [PDF]
Tetracera macrophylla is a valuable medicinal plant used traditionally for the treatment of various ailments. The crude ethanol extract was analyzed for its total phenolic and flavonoid contents.
Ahmed, Qamar Uddin +6 more
core +1 more source
Microbiome-derived metabolites in early to mid-pregnancy and risk of gestational diabetes: a metabolome-wide association study. [PDF]
BACKGROUND: Pre-diagnostic disturbances in the microbiome-derived metabolome have been associated with an increased risk of diabetes in non-pregnant populations.
Susarla SM +7 more
europepmc +3 more sources
Nucleophile-Catalyzed Additions to Activated Triple Bonds. Protection of Lactams, Imides, and Nucleosides with MocVinyl and Related Groups [PDF]
Additions of lactams, imides, (S)-4-benzyl-1,3-oxazolidin-2-one, 2-pyridone, pyrimidine-2,4-diones (AZT derivatives), or inosines to the electron-deficient triple bonds of methyl propynoate, tert-butyl propynoate, 3-butyn-2-one, N-propynoylmorpholine, or
Adler M. +71 more
core +2 more sources
Analysis of prescription pattern of antihypertensives in various stages of chronic kidney disease [PDF]
Background: Chronic kidney disease (CKD) is an emerging health problem and is one of the major causes of mortality. Hypertension is closely linked with CKD and both these conditions cause severe cardiovascular events.
Jayakumar, K. P. +2 more
core +2 more sources

