Results 11 to 20 of about 18,313 (167)
Imidazodiazepinediones: a new class of adenosine receptor antagonists.
Journal of Medicinal Chemistry, 1990 A series of imidazo[4,5-e][l-4]diazepine-5,8-diones were synthesized from hypoxanthines. Certain of these cyclic homologues of caffeine, theophylline, theobromine, 3-isobutyl-l-methylxanthine, and enprofylline were inhibitors of binding of adenosine ...
John W. Daly +2 more
semanticscholar +2 more sources
Hypoxanthine as a Measurement of Hypoxia [PDF]
Pediatric Research, 1975 The hypoxanthine concentration in plasma was found to be a sensitive parameter of hypoxia of the fetus and the newborn infant. The plasma level of hypoxanthine in the umbilical cord in 29 newborn infants with normal delivery varied between 0 and 11.0 mumol/liter with a mean of 5.8 mumol/liter, SD 3.0 mumol/liter.
openaire +2 more sources
Hypoxanthine uptake by human erythrocytes [PDF]
FEBS Letters, 1979 It is well established that the uptake of hypoxan- thin, by human erythrocytes is mediated by its incorporation into IMP [ 11. The synthesis of this nucleotide is dependent on the intracellular availability of 5phosphoribosyl o-1-pyrophosphate (PRPP) and on the activity of hypoxanthine-guanine phospho- ribosyltransferase (HGPRT) [ 11.
GIACOMELLO, Alessandro +1 more
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SLC23A3 is a renal hypoxanthine transporter
Nucleosides, Nucleotides & Nucleic Acids, 2022 LLC-PK1 renal cells show Na+-dependent and Na+-independent hypoxanthine uptake. While the latter is inhibited by adenine, neither are inhibited by xanthine. In rats, intestinal Na+-dependent hypoxanthine transporter Slc23a4 is not expressed in the kidney, and its action is inhibited by xanthine.
Makoto Hosoyamada +5 more
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The chemical simulation of the “atp-imidazole” cycle
, 1986 The synthetic strategy inherent in the "ATP-Imidazole" cycle and centred around the vicinal disposition of -NH2 and -CONH2 functions, has been demonstrated with anthranilamide (2) and 1-benzyl-5-aminoimidazole-4-carboxamide (1) as regeneratable carriers ...
Ranganathan, Darshan +9 more
core +1 more source
FLAVIN-HYPOXANTHINE DINUCLEOTIDE
THE JOURNAL OF VITAMINOLOGY, 1957 1. FHD was synthesized from FAD by deamination with nitrous acid and the product was first isolated as barium salt. The yield and purity were, however, unsatisfactory by this method. Therefore, the product was extracted with cresol, followed by transfer in aqueous phase, and by subjecting to column chromatography, FHD was obtained in high purity in ...
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THE ESTIMATION OF HYPOXANTHINE
Journal of Biological Chemistry, 1942 In a previous paper there was described a procedure for the isolation of the purines in a form suitable for the quantitative determination of the individual substances (1). A later publication reported a method for the separation of adenine and hypoxanthine and the determination of the adenine by precipitation of adenine picrate and titration of the ...
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, 1993 Several 2- or 8-n-alkyl-hypoxanthines and a 2,8-di-n-pentyl-hypoxanthine were synthesized and tested as substrates or inhibitors of Xanthine Oxidase (XO).
Livi O +5 more
core
, 1993 Several 2- or 8-n-alkyl-hypoxanthines and a 2,8-di-n-pentyl-hypoxanthine were synthesized and tested as substrates or inhibitors of Xanthine Oxidase (XO).
BIAGI G +5 more
core
Rapid detection of hypoxanthine-guanine phosphoribosyltransferase on cellogel
, 1974 A simple, fast and direct staining method for the detection of hypoxanthineguanine phosphoribosyltransferase is described. It is based on the conversion of inosine monophosphate to hypoxanthine, which is then enzymatically oxidized.
Khan, P.M. +2 more
core