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Genetic heterogeneity at the locus for hypoxanthine-guanine phosphoribosyltransferase.

Ciba Foundation symposium, 1977
The purine phosphoribosyltransferases have emerged as important enzymes in the metabolic economy of the developing human. Hypoxanthine-guanine phosphoribosyltransferase (HGPRT, EC 2.4.2.8) catalyses the conversion of hypoxanthine and guinine into their respective nucleotides.
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