Results 231 to 240 of about 51,551 (285)

Purine metabolism: a pan-cancer metabolic dysregulation across circulation and tissues. [PDF]

Mol Cancer
Yu M, Liu C, Cao M, Yang D, Wang T, Xu J, Zhu D, Wang G, Aa J, Zhu W.   +9 more
europepmc   +1 more source

From niche to blockbuster: a greater role for allopurinol in maintenance treatment of acute lymphoblastic leukemia. [PDF]

Haematologica
Stanulla M.
europepmc   +1 more source

Guanine storage vacuoles sequester guanine crystals and serve as nitrogen reserves in <i>Chlamydomonas reinhardtii</i>. [PDF]

Proc Natl Acad Sci U S A
Goodenough U, Roth R, Lee JH.
europepmc   +1 more source

Significance and amplification methods of the purine salvage pathway in human brain cells. [PDF]

J Biol Chem
Sekine M, Fujiwara M, Okamoto K, Ichida K, Nagata K, Hille R, Nishino T.   +6 more
europepmc   +1 more source

Whole-genome analysis of Bacillus paranthracis YC06 isolated from healthy individual feces for biodegrading inosine and guanosine. [PDF]

BMC Microbiol
Cao X, Zhang Y, Xu Q, Yan H.
europepmc   +1 more source

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Transformation of the gene for hypoxanthine phosphoribosyltransferase

Somatic Cell Genetics, 1979
Purified DNA from wild-type Chinese ovary (CHO) cells has been used to transform three hypoxanthine phosphoribosyltransferase (HPRT) deficient murine cell mutants to the enzyme positive state. Transformants appeared at an overall frequency of 5 x 10(-8) colonies/treated cell and expressed CHO HPRT activity as determined by electrophoresis.
L. H. Graf, G. Urlaub, L. Chasin
semanticscholar   +3 more sources

Unapparent hypoxanthine-guanine phosphoribosyltransferase deficiency

Clinica Chimica Acta, 2017
Complete deficiency of hypoxanthine-guanine phosphoribosyltransferase (HPRT) activity causes Lesch Nyhan disease (LND), characterized by hyperuricemia, severe action dystonia, choreoathetosis, ballismus, cognitive and attention deficit and self-injurious behavior.
R J, Torres, S, Puente, A, Menendez, N, Fernandez-Garcia   +3 more
openaire   +2 more sources

Facilitated Purification of Hypoxanthine Phosphoribosyltransferase

Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1976
Three major approaches to the complete purification of hypoxanthine phosphoribosyltransferase from human erythrocytes and rat brain are described. Preparative isoelectric focusing which has been used for the isolation of the human enzyme was not fully successful in the case of rat brain.
W, Gutensohn, M, Huber, H, Jahn
openaire   +2 more sources