Human hypoxanthine-guanine phosphoribosyltransferase.
A mutant form of human hypoxanthine-guanine phosphoribosyltransferase (HPRTToronto) was isolated from erythrocytes of a male patient with gout due to a partial deficiency of enzyme activity. The tryptic peptides of HPRTToronto were mapped by reverse-phase high pressure liquid chromatography in an attempt to define the precise abnormality in its primary
J M, Wilson +3 more
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Inhibition and Mechanism of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase. [PDF]
V T Minnow Y +9 more
europepmc +3 more sources
Hypoxanthine phosphoribosyl transferase 1 metabolizes temozolomide to activate AMPK for driving chemoresistance of glioblastomas. [PDF]
Yin J +19 more
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Three Hypoxanthine Derivatives from the Marine Cyanobacterium Okeania hirsuta
Three novel hypoxanthine derivatives (1–3) were obtained from the Okinawan cyanobacterium Okeania hirsuta. The structures of these compounds were elucidated mainly based on the spectroscopic data, including 1D and 2D NMR, as well as high-resolution mass ...
Ryoya Kawabe +5 more
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FLAVIN-HYPOXANTHINE DINUCLEOTIDE
1. FHD was synthesized from FAD by deamination with nitrous acid and the product was first isolated as barium salt. The yield and purity were, however, unsatisfactory by this method. Therefore, the product was extracted with cresol, followed by transfer in aqueous phase, and by subjecting to column chromatography, FHD was obtained in high purity in ...
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Biochar offers promising solutions for agricultural sustainability, yet the intricate mechanisms governing rhizosphere metabolite-microbe-soil interactions remain poorly understood. Through a decade-long field experiment, the effects of sustained biochar
Di Wu +8 more
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Hypoxanthine uptake by human erythrocytes [PDF]
It is well established that the uptake of hypoxan- thin, by human erythrocytes is mediated by its incorporation into IMP [ 11. The synthesis of this nucleotide is dependent on the intracellular availability of 5phosphoribosyl o-1-pyrophosphate (PRPP) and on the activity of hypoxanthine-guanine phospho- ribosyltransferase (HGPRT) [ 11.
GIACOMELLO, Alessandro +1 more
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Downregulation of Peroxidase Activity of Platinum Cube Enables Minute–Time Scale Colorimetric Signaling of Hypoxanthine for Fish Freshness Monitoring [PDF]
Xiaoming Ma +10 more
openalex +1 more source
Bacillus Subtilis 29784 as a Feed Additive for Broilers Shifts the Intestinal Microbial Composition and Supports the Production of Hypoxanthine and Nicotinic Acid [PDF]
Pearl Choi +9 more
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Exploiting Purine as an Internal Standard for SERS Quantification of Purine Derivative Molecules Released by Bacteria. [PDF]
Cheng HW, Tsai HM, Wang YL.
europepmc +1 more source

