Anti-inflammatory potential of Penicillium brefeldianum endophytic fungus supported with phytochemical profiling. [PDF]
Saleh A +9 more
europepmc +1 more source
Influence of DNA structure on hypoxanthine and 1,N6-ethenoadenine removal by murine 3-methyladenine DNA glycosylase [PDF]
Michael D. Wyatt
openalex +1 more source
Narrative review of strategies for blood product shelf‐life extension
Transfusion, EarlyView.
Mike Akaraphanth +7 more
wiley +1 more source
ITM2B Truncation Promotes Migrasome Formation to Accelerate Renal Cell Carcinoma Growth
This study identifies truncated ITM2B as a regulator of migrasome formation in renal cell carcinoma (RCC) cells. The ITM2B truncation not only facilitates migrasome formation by recruiting TSPAN4, but also sorts active caspase‐7 into migrasomes. The internalization of active caspase‐7‐enriched migrasomes by macrophages stimulates IL‐6 secretion to ...
Qi‐tao Chen +10 more
wiley +1 more source
A Retrospective Look at the Impact of Binding Site Environment on the Optimization of TRPA1 Antagonists. [PDF]
Villemure E +9 more
europepmc +1 more source
Graphical representation of spasticity and medication changes. (A) Temporal course of lower limb spasticity measured by MAS scores. Following initiation of allopurinol 300 mg daily at baseline (red dashed line), there was a rapid and sustained improvement in spasticity from severe (MAS = 4) to mild (MAS = 1.8) over 12 months of follow‐up, represented ...
Ziad W. Elmezayen +3 more
wiley +1 more source
Overview of study design. Metagenomic and plasma/fecal metabolomic studies were performed in 44 NSCLC patients who underwent neoadjuvant tislelizumab therapy plus platinum ‐ based doublet chemotherapy. Abstract Background Neoadjuvant anti‐programmed cell death 1 (PD‐1) immunochemotherapy has shown promising efficiency in the treatment of early‐stage ...
Ailing Cao +11 more
wiley +1 more source
Profiles and integration of the gut microbiome and fecal metabolites in severe intrahepatic cholestasis of pregnancy. [PDF]
Li X +8 more
europepmc +1 more source
Serum Uric Acid as a Mediator of Insulin Resistance: Molecular Mechanisms and Metabolic Pathways
Elevated SUA can lead to oxidative stress, endothelial dysfunction, inflammation and impaired function of adipocytes—all of which collectively impede insulin receptor activity and downstream signalling. Key pathways involved include activation of the NLRP3 inflammasome, suppression of AMPK and induction of mitochondrial dysfunction.
Nurshad Ali
wiley +1 more source
Metabolic Signature of Energy Metabolism Alterations and Excess Nitric Oxide Production in Culture Media Correlate with Low Human Embryo Quality and Unsuccessful Pregnancy. [PDF]
Pallisco R +13 more
europepmc +1 more source

