Results 51 to 60 of about 503 (139)

Minimizing quantification uncertainty in nanoplasmonic platforms: Multifunctional MoS2‐integration for precise biomarker determination

InfoMat, Volume 8, Issue 3, March 2026.
The multifunctional integration of MoS2 into the SERS platform addresses key limitations in accurate quantification. Atomically thin MoS2 reduces spot‐to‐spot variations via plasmonic calibration and improves quantification reliability by ensuring consistent signal changes with analyte concentration.
Seungkyun Lee, Seongdae Kwon, Seunghee H. Cho, Minjae Ku, Young Woo Han, Gunwoo Jo, Jeongwon Park, Hanhwi Jang, Kibum Kang, Yeon Sik Jung   +9 more
wiley   +1 more source

Retinal Capillary Density Reduction Contributes to Dysthyroid Optic Neuropathy via an L‐Arginine‐NO Pathway: A Metabonomics and Clinical Trial Study

MedComm, Volume 7, Issue 3, March 2026.
Oxidative stress induces endothelial nitric oxide synthase (eNOS) uncoupling and L‐arginine depletion, reducing nitric oxide (NO) bioavailability in vascular endothelium and contributing to decreased retinal capillary density (RCD) in dysthyroid optic neuropathy (DON).
Yunhai Tu, Congcong Yan, Lu Chen, Weijie Liu, Xiaozhou Hu, Mengyuan Gao, Wei Rao, Jiayi Zhang, Junye Zhu, Hui Wu, Kang Zhang, Meng Zhou, Wencan Wu   +12 more
wiley   +1 more source

Abnormalities of neural stem cells in Lesch-Nyhan disease. [PDF]

J Neurogenet, 2022
Dinasarapu AR, Sutcliffe DJ, Seifar F, Visser JE, Jinnah HA.   +4 more
europepmc   +1 more source

Trans‐Omics Integration Reveals That the Kidney Contributes to Systemic Aging via Sexually Dimorphic Accumulation of Glycosphingolipids

MedComm, Volume 7, Issue 3, March 2026.
Female‐specific renal GluCer accumulation disrupts mitochondrial quality control via a conserved purine‐mTORC1 pathway, triggering a wave of uremic toxins into the systemic circulation that constitutes a female‐biased vulnerability toward renal‐driven multiorgan senescence.
Zhen Ni, Chenyin Cao, Yanlin Tian, Jinming Mu, He Tian, Zehua Wang, Shaohua Zhang, Mingjun Cao, Yuntian Yang, Wei Ling Florence Lim, Jingkang Cui, Huan Sun, Huan Miao, Yuan Wang, Jie Du, Timothy Kwok, Huan Chen, Sin Man Lam, Guanghou Shui   +18 more
wiley   +1 more source

High-risk genotypes for type 1 diabetes are associated with the imbalance of gut microbiome and serum metabolites. [PDF]

Front Immunol, 2022
Yue T, Tan H, Wang C, Liu Z, Yang D, Ding Y, Xu W, Yan J, Zheng X, Weng J, Luo S.   +10 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Virtual Twin Approach for Fludarabine Dosing in Pediatric Hematopoietic Stem Cell Transplantation

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.
ABSTRACT Fludarabine (Flu), administered as a prodrug Flu monophosphate, is a lymphodepleting agent used prior to hematopoietic stem cell transplantation (HSCT) which exhibits substantial pharmacokinetics (PK) variability, contributing to suboptimal outcomes.
Mourad Mseddi, Christa Nath, Khalil Ben Hassine, Vid Mlakar, Yvonne Gloor, Fanny Gonzales, Chakradhara Rao S. Uppugunduri, Youssef Daali, Steven Keogh, Marc Ansari   +9 more
wiley   +1 more source

Mutation of OsSAC3, Encoding the Xanthine Dehydrogenase, Caused Early Senescence in Rice. [PDF]

Int J Mol Sci, 2022
Xie Z, Zhao B, Zhang M, Sang X, Zhao F, Feng P, He G, Zhu X.   +7 more
europepmc   +1 more source

THE ESTIMATION OF HYPOXANTHINE

Journal of Biological Chemistry, 1942
In a previous paper there was described a procedure for the isolation of the purines in a form suitable for the quantitative determination of the individual substances (1). A later publication reported a method for the separation of adenine and hypoxanthine and the determination of the adenine by precipitation of adenine picrate and titration of the ...
openaire   +1 more source

Assessment of the influence on left ventricle by potassium oxonate and hypoxanthine-induced chronic hyperuricemia. [PDF]

Exp Biol Med (Maywood), 2023
Lin C, Zheng Q, Li Y, Wu T, Luo J, Jiang Y, Huang Q, Yan C, Zhang L, Zhang W, Liao H, Yang Y, Pang J.   +12 more
europepmc   +1 more source

Capsaicin Ameliorates High-Fat Diet-Induced Atherosclerosis in ApoE^-/- Mice via Remodeling Gut Microbiota. [PDF]

Nutrients, 2022
Dai Z, Li S, Meng Y, Zhao Q, Zhang Y, Suonan Z, Sun Y, Shen Q, Liao X, Xue Y.   +9 more
europepmc   +1 more source