Results 61 to 70 of about 579 (178)

Stress exposure in the mdx mouse model of Duchenne muscular dystrophy provokes a widespread metabolic response

open access: yesThe FEBS Journal, EarlyView.
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley   +1 more source

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

open access: yesJournal of Anatomy, EarlyView.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann   +8 more
wiley   +1 more source

Metabolism of hypoxanthine in wheat shoots

open access: yesActa Societatis Botanicorum Poloniae, 2015
The incorporation of [<sup>14</sup>C] glycine and [8-<sup>l4</sup>C] hypoxanthine to some purine derivatives in overground parts of wheat seedlings was studied. It was found that adenylic acid could be synthesized from glycine and also from free hypoxanthine and in both processes inosinic acid is an intermediate metabolite.
openaire   +4 more sources

PhD [PDF]

open access: yes, 2007
dissertationMethylation of formycin under non-basic reaction conditions has afforded 4-methylformycin and 6-methylformycin. The structures assigned to these two mono-N0methyl isomers of formycin were based on ultraviolet and nuclear magnetic resonance ...
Lewis, Arthur Frank
core  

Study-based registers of randomised controlled trials: the premise and increasing sophistication of data supply for evidence synthesis [PDF]

open access: yes, 2020
Extended Abstract Summary Although narrative reviews remain important, overviewing literature often now takes some form of systematic approach. Pivotal to being systematic is the searching and, with that, the role of Information Specialists.
Shokraneh, Farhad
core  

Elevated cortisol concentration in preterm sheep fetuses impacts heart development

open access: yesExperimental Physiology, EarlyView.
Abstract The prepartum rise in cortisol promotes cardiac development and maturation. Here, we investigated the impact of elevated circulating cortisol during mid‐late gestation on cardiac growth and metabolism in fetal sheep. Saline or cortisol (2–3 mg in 4.4 mL/24 h) was infused into the fetal jugular vein from 109 to 116 days gestation (dG, term ...
Reza Amanollahi   +9 more
wiley   +1 more source

Update on metabolomic findings in COPD patients. [PDF]

open access: yesERJ Open Res, 2023
Gea J   +3 more
europepmc   +1 more source

Adjacent long non-coding RNA PVT1 and MYC co-operate in breast cancer with gain of 8q24 [PDF]

open access: yes, 2013
University of Minnesota Ph.D. dissertation. August 2013. Major: Molecular, Cellular, Developmental Biology and Genetics. Advisor: Anindya Bagchi. 1 computer file (PDF); viii, 107 pages, appendices A-B.Copy number gain of 8q24 is a common structural ...
Tseng, Yuen-Yi
core  

Fetal glucose availability: a key regulator of the metabolic, hormonal and contractility profiles of the fetal sheep heart

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend To investigate the role of glucose availability in fetal left ventricle (LV) development, this study assessed whether maternal late gestation undernutrition (LGUN; 50% of Control diet) induced alterations in the contractility, metabolic, and hormonal profile can be ameliorated in LGUN fetuses receiving glucose infusion (LGUN+G ...
Melanie R. Bertossa   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy