Results 61 to 70 of about 579 (178)
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley +1 more source
Evaluating the Accuracy of the QCEIMS Approach for Computational Prediction of Electron Ionization Mass Spectra of Purines and Pyrimidines. [PDF]
Lee J+4 more
europepmc +1 more source
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann+8 more
wiley +1 more source
Metabolism of hypoxanthine in wheat shoots
The incorporation of [<sup>14</sup>C] glycine and [8-<sup>l4</sup>C] hypoxanthine to some purine derivatives in overground parts of wheat seedlings was studied. It was found that adenylic acid could be synthesized from glycine and also from free hypoxanthine and in both processes inosinic acid is an intermediate metabolite.
openaire +4 more sources
dissertationMethylation of formycin under non-basic reaction conditions has afforded 4-methylformycin and 6-methylformycin. The structures assigned to these two mono-N0methyl isomers of formycin were based on ultraviolet and nuclear magnetic resonance ...
Lewis, Arthur Frank
core
Study-based registers of randomised controlled trials: the premise and increasing sophistication of data supply for evidence synthesis [PDF]
Extended Abstract Summary Although narrative reviews remain important, overviewing literature often now takes some form of systematic approach. Pivotal to being systematic is the searching and, with that, the role of Information Specialists.
Shokraneh, Farhad
core
Elevated cortisol concentration in preterm sheep fetuses impacts heart development
Abstract The prepartum rise in cortisol promotes cardiac development and maturation. Here, we investigated the impact of elevated circulating cortisol during mid‐late gestation on cardiac growth and metabolism in fetal sheep. Saline or cortisol (2–3 mg in 4.4 mL/24 h) was infused into the fetal jugular vein from 109 to 116 days gestation (dG, term ...
Reza Amanollahi+9 more
wiley +1 more source
Update on metabolomic findings in COPD patients. [PDF]
Gea J+3 more
europepmc +1 more source
Adjacent long non-coding RNA PVT1 and MYC co-operate in breast cancer with gain of 8q24 [PDF]
University of Minnesota Ph.D. dissertation. August 2013. Major: Molecular, Cellular, Developmental Biology and Genetics. Advisor: Anindya Bagchi. 1 computer file (PDF); viii, 107 pages, appendices A-B.Copy number gain of 8q24 is a common structural ...
Tseng, Yuen-Yi
core
Abstract figure legend To investigate the role of glucose availability in fetal left ventricle (LV) development, this study assessed whether maternal late gestation undernutrition (LGUN; 50% of Control diet) induced alterations in the contractility, metabolic, and hormonal profile can be ameliorated in LGUN fetuses receiving glucose infusion (LGUN+G ...
Melanie R. Bertossa+10 more
wiley +1 more source