Results 151 to 160 of about 1,301,346 (361)

Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression. [PDF]

, 1996
Edi Brogi, Gina C. Schatteman, Ta‐Peng Wu, Eunyoung Kim, Lyuba Varticovski, Bruce A. Keyt, Jeffrey M. Isner   +6 more
openalex   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Anoxic induction of a sarcoma virus-related VL30 retrotransposon is mediated by a cis-acting element which binds hypoxia-inducible factor 1 and an anoxia-inducible factor [PDF]

, 1995
Scott Estes, Daniel L. Stoler, Garth R. Anderson   +2 more
openalex   +1 more source

Cellular adaptation to hypoxia through hypoxia inducible factors and beyond

Nature reviews. Molecular cell biology, 2020
Pearl Lee, N. Chandel, M. C. Simon
semanticscholar   +1 more source

Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy

Advanced Functional Materials, EarlyView.
Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi, Elias Huber, Leonie Karr, Johnny Tong, Andreas Richard Bausch, Friedrich Christian Simmel, Karen Alim   +6 more
wiley   +1 more source

Cellular and developmental control of O₂ homeostasis by hypoxia-inducible factor 1α [PDF]

, 1998
Narayan V. Iyer, Lori E. Kotch, Faton Agani, Sandra W. Leung, Erik Laughner, Roland H. Wenger, Max Gassmann, John D. Gearhart, Ann M. Lawler, Aimee Y. Yu, Gregg L. Semenza   +10 more
openalex   +1 more source

Hypoxia-inducible factors in T lymphocyte differentiation and function. A Review in the Theme: Cellular Responses to Hypoxia.

American Journal of Physiology - Cell Physiology, 2015
Low oxygen concentrations or hypoxia is a trait common to inflamed tissues. Therefore it is not surprising that pathways of hypoxic stress response, largely governed by hypoxia-inducible factors (HIF), are highly relevant to the proper function of immune
Jin-Hui Tao, J. Barbi, F. Pan
semanticscholar   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Differential expression of hypoxia-inducible factor 1α in non-small cell lung cancer and small cell lung cancer

Clinics, 2012
OBJECTIVES: The aim of this study was to compare the expression of hypoxia-inducible factor 1α and vascular endothelial growth factor in small cell lung cancer and subtypes of non-small cell lung cancer and examine their relationships with ...
Eleni Karetsi, Maria G. Ioannou, Theodora Kerenidi, Markos Minas, Paschalis A. Molyvdas, Konstantinos I. Gourgoulianis, Efrosyni Paraskeva   +6 more
doaj   +1 more source

Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α [PDF]

, 1999
Aimee Y. Yu, Larissa A. Shimoda, Narayan V. Iyer, David L. Huso, Xing Sun, Rita McWilliams, Terri H. Beaty, James S.K. Sham, Charles Wiener, J. T. Sylvester, Gregg L. Semenza   +10 more
openalex   +1 more source