Results 191 to 200 of about 1,344,802 (358)

Hypoxia-inducible factor as a transcriptional factor regulating gene expression in cancer cells [PDF]

, 2011
Ewelina Dondajewska, Wiktoria Maria Suchorska   +1 more
openalex   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Hypoxia‐induced CXC chemokine ligand 14 expression drives protumorigenic effects through activation of insulin‐like growth factor‐1 receptor signaling in glioblastoma

, 2022
Sung‐Tai Wei, Jung‐Ying Chiang, Hwai‐Lee Wang, Fu‐Ju Lei, Yen‐Chih Huang, Chi‐Chuan Wang, Der‐Yang Cho, Chia‐Hung Hsieh   +7 more
openalex   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy.

TIPS - Trends in Pharmacological Sciences, 2012
G. Semenza
semanticscholar   +1 more source

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun, XueBo Wei, ZhuoYang Song, JunJun Luo, JingYi Ye, YinNan Zhang, LiFei Zhu, Jie Gao, Hongyu Zhang, Hong Zhu, Xin Wang, Ke Xu   +11 more
wiley   +1 more source

The impact of hypoxia-inducible factors in the pathogenesis of kidney diseases: a link through cell metabolism. [PDF]

Kidney Res Clin Pract, 2023
Foresto-Neto O, da Silva ARPA, Cipelli M, Santana-Novelli FPR, Camara NOS.   +4 more
europepmc   +1 more source

Hypoxia-Inducible Factors: Master Regulators of Cancer Progression.

Trends in Cancer, 2016
L. Schito, G. Semenza
semanticscholar   +1 more source

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source

Saururus cernuus lignans—Potent small molecule inhibitors of hypoxia-inducible factor-1

, 2005
Chowdhury Faiz Hossain, Yong-Pil Kim, Scott R. Baerson, Lei Zhang, Richard K. Bruick, Kaleem A. Mohammed, Ameeta K. Agarwal, Dale G. Nagle, Yu-Dong Zhou   +8 more
openalex   +1 more source