Results 251 to 260 of about 1,344,802 (358)

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

The role of hypoxia-inducible factors 1 and 2 in the pathogenesis of diabetic kidney disease. [PDF]

J Nephrol
Kleibert M, Tkacz K, Winiarska K, Małyszko J, Cudnoch-Jędrzejewska A.   +4 more
europepmc   +1 more source

Mutual Regulation between Redox and Hypoxia-Inducible Factors in Cardiovascular and Renal Complications of Diabetes. [PDF]

Antioxidants (Basel), 2022
Iacobini C, Vitale M, Haxhi J, Pesce C, Pugliese G, Menini S.   +5 more
europepmc   +1 more source

Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1α and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells [PDF]

, 2005
Qunzhou Zhang, Xudong Tang, Qing‐Yi Lu, Zuo‐Feng Zhang, Jimmy J. Brown, Anh D. Lê   +5 more
openalex   +1 more source

Data from Thioredoxin-1 Modulates Transcription of Cyclooxygenase-2 via Hypoxia-Inducible Factor-1α in Non–Small Cell Lung Cancer

, 2023
Ildiko Csiki, Kiyoshi Yanagisawa, Nobuhiro Haruki, Sorena Nadaf, Jason D. Morrow, David H. Johnson, David P. Carbone   +6 more
openalex   +1 more source

Hypoxia-Inducible Factor-1 [PDF]

, 2020
openaire   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Recent Insights into Roles of Hypoxia-Inducible Factors in Retinal Diseases. [PDF]

Int J Mol Sci
Lee D, Tomita Y, Miwa Y, Kunimi H, Nakai A, Shoda C, Negishi K, Kurihara T.   +7 more
europepmc   +1 more source

Therapeutic potential of topical administration of acriflavine against hypoxia-inducible factors for corneal fibrosis. [PDF]

Front Pharmacol, 2022
Zhu S, Shan H, Li J, Pan L, Wang S, Zhu J, Guo H, Mi F, Wu X, Yin J, Pang K.   +10 more
europepmc   +1 more source

Comparative effectiveness of hypoxia-inducible factor prolyl hydroxylase inhibitors versus erythropoiesis-stimulating agents on prognosis in non-dialysis chronic kidney disease: a propensity-matched cohort study

Hou, Yi-Chou, Wu, Chia-Lin, Tseng, Wei-Cheng, Wang, Joshua, Lu, Kuo-Cheng, Zheng, Cai-Mei, Liu, Jia-Sin, Kuo, Ko-Lin, Tarng, Der-Cherng   +8 more
openalex   +1 more source