Results 251 to 260 of about 1,301,346 (361)

Thrombin Activates the Hypoxia-Inducible Factor-1 Signaling Pathway in Vascular Smooth Muscle Cells [PDF]

, 2001
Agnes Görlach, Isabel Diebold, Valérie B. Schini‐Kerth, Utta Berchner‐Pfannschmidt, U Roth, Ralf P. Brandes, Thomas Kietzmann, Rudi Busse   +7 more
openalex   +1 more source

Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer.

Pharmacology and Therapeutics, 2016
C. Wigerup, S. Påhlman, D. Bexell
semanticscholar   +1 more source

Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery

Advanced Science, EarlyView.
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou, Xin‐Ge Wang, Xuan‐Ren Shi, Shu‐Ting Sun, Jing Mi, Xiao‐Peng Zhang, Bin‐Cheng Yin, Ying Zhou, Bang‐Ce Ye   +8 more
wiley   +1 more source

Recent Insights into Roles of Hypoxia-Inducible Factors in Retinal Diseases. [PDF]

Int J Mol Sci
Lee D, Tomita Y, Miwa Y, Kunimi H, Nakai A, Shoda C, Negishi K, Kurihara T.   +7 more
europepmc   +1 more source

Therapeutic potential of topical administration of acriflavine against hypoxia-inducible factors for corneal fibrosis. [PDF]

Front Pharmacol, 2022
Zhu S, Shan H, Li J, Pan L, Wang S, Zhu J, Guo H, Mi F, Wu X, Yin J, Pang K.   +10 more
europepmc   +1 more source

The transcription factor EPAS-1/hypoxia-inducible factor 2α plays an important role in vascular remodeling

, 2000
Jun Peng, Liyong Zhang, Linsay Drysdale, Guo‐Hua Fong   +3 more
openalex   +1 more source

Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1α [PDF]

, 2001
David A. Elson, Gavin Thurston, Eric Huang, David G. Ginzinger, Donald M. McDonald, Randall S. Johnson, Jeffrey M. Arbeit   +6 more
openalex   +1 more source

Polydopamine Nanohydrogel Decorated Adhesive and Responsive Hierarchical Microcarriers for Deafness Protection

Advanced Science, EarlyView.
A type of polydopamine (PDA) nanogel decorated adhesive and responsive hierarchical microcarriers for ALA delivery and deafness prevention. PDA@microcarriers can protect the encapsulated drugs from external disturbances and prolong their retention time in the inner ear.
Hong Chen, Hui Zhang, Jiayi Li, Xianmei Wei, Chenjie Yu, Yuanjin Zhao, Maoli Duan, Xiaoyun Qian, Xia Gao   +8 more
wiley   +1 more source

Targeting hypoxia-inducible factors in malignancies caused by Kaposis sarcoma associated herpesvirus. [PDF]

Glob Health Med
Davis DA, Shrestha P, Yarchoan R.
europepmc   +1 more source

Hypoxic Regulation of Inducible Nitric Oxide Synthase via Hypoxia Inducible Factor-1 in Cardiac Myocytes

, 2000
Frank Jung, Lisa A. Palmer, Nan Zhou, Roger A. Johns   +3 more
openalex   +1 more source