Results 261 to 270 of about 1,301,346 (361)

Identification of Hypoxia-inducible Factor 1 Ancillary Sequence and Its Function in Vascular Endothelial Growth Factor Gene Induction by Hypoxia and Nitric Oxide [PDF]

, 2001
Hideo Kimura, Alessandro Weisz, Tsutomu Ogura, Yoshiaki Hitomi, Yukiko Kurashima, Kouichi Hashimoto, Fulvio D’Acquisto, Masatoshi Makuuchi, Hiroyasu Esumi   +8 more
openalex   +1 more source

Tale of two transcription factors: NF-кB and HIF crosstalk [PDF]

, 2013
Bandarra, D., Rocha, S.
core   +1 more source

Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3‐Regulated HIF1A/HMOX1 Signaling Pathway

Advanced Science, EarlyView.
This study reveals that histone lactylation, a modification derived from lactate, plays a crucial role in ferroptosis resistance in ectopic endometrial stromal cells. This resistance is mediated via the HIF1A/HMOX1 pathway regulated by METTL3. In vivo, a combination of 2‐DG and erastin shows promise as an effective treatment for endometriosis ...
Zongwen Liang, Jinming Liu, Yanling Gou, Honglin Wang, Zhi Li, Yingying Cao, Huiyan Zhang, Ruru Bai, Zongfeng Zhang   +8 more
wiley   +1 more source

Hypoxia, hypoxia-inducible factors and inflammatory bowel diseases. [PDF]

Gastroenterol Rep (Oxf)
Hou F, Bian X, Jing D, Gao H, Zhu F.
europepmc   +1 more source

The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function. [PDF]

Front Immunol, 2023
Vanderhaeghen T, Timmermans S, Eggermont M, Watts D, Vandewalle J, Wallaeys C, Nuyttens L, De Temmerman J, Hochepied T, Dewaele S, Berghe JV, Sanders N, Wielockx B, Beyaert R, Libert C.   +14 more
europepmc   +1 more source

Hypoxia-Inducible Factor 1-Mediated Inhibition of Peroxisome Proliferator-Activated Receptor α Expression During Hypoxia [PDF]

, 2001
Sailaja Narravula, Sean P. Colgan
openalex   +1 more source

Hypoxia‐inducible factors as neuroprotective agent in Alzheimer's disease

Clinical and Experimental Pharmacology and Physiology, 2017
B. Ashok, T. Ajith, Senthilkumar Sivanesan   +2 more
semanticscholar   +1 more source

METTL14‐Mediated M6A Modification of LINC01094 Induces Glucose Metabolic Reprogramming in Breast Cancer by Recruiting the PKM2/JMJD5 Complex

Advanced Science, EarlyView.
METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang, Zhaoxin Gao, Ruinan Zhao, Pan Zhou, Jingxi Chen, Hui Zhang, Yawen Wang, Wenjie Zhu, Peng Gao   +8 more
wiley   +1 more source

Clinical investigation of hypoxia-inducible factors: getting there. [PDF]

J Clin Invest
Semenza GL.
europepmc   +1 more source

Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain [PDF]

, 2001
Emma C. Vaux, Eric Metzen, Kay M. Yeates, Peter J. Ratcliffe   +3 more
openalex   +1 more source