Results 171 to 180 of about 939,686 (311)

Use of a computer model in the understanding of erythropoietic control mechanisms [PDF]

During an eight-week visit approximately 200 simulations using the computer model for the regulation of erythopoiesis were carries out in four general areas: with the human model simulating hypoxia and dehydration, evaluation of the simulation of ...
Dunn, C. D. R.
core   +1 more source

Glucocorticoids exacerbate hypoxia-induced expression of the pro-apoptotic gene Bnip3 in the developing cortex

, 2006
Ursula S. Sandau, Robert J. Handa
openalex   +1 more source

Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing

Advanced Materials, EarlyView.
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...
Yedong Ma, Chengke Xie, Chengyu Liao, Binting Huang, Siqi Liu, Junhua Kong, Xiaotong Fan, Zibiao Li, Shi Chen, Chaobin He   +9 more
wiley   +1 more source

EFFECT OF I.V. MIDAZOLAM ON THE VENTILATORY RESPONSE TO SUSTAINED HYPOXIA IN MAN

, 1991
Albert Dahan, Denham S. Ward
openalex   +1 more source

Hypoxia Induces VEGF-C Expression in Metastatic Tumor Cells via a HIF-1α-Independent Translation-Mediated Mechanism [PDF]

, 2014
Florent Morfoisse, Anna Kuchnio, Clément Frainay, Anne Gomez‐Brouchet, Marie‐Bernadette Delisle, Stefano Marzi, Anne‐Catherine Helfer, Fransky Hantelys, Françoise Pujol, Julie Guillermet‐Guibert, Corinne Bousquet, Mieke Dewerchin, Stéphane Pyronnet, Anne‐Catherine Prats, Peter Carmeliet, Barbara Garmy‐Susini   +15 more
openalex   +1 more source

Tailoring Advanced Metal‐Based Nanomedicines for Adaptable Nanodynamic Disease Therapies and Theranostics

Advanced Materials, EarlyView.
This review summarizes recent advances in metal‐based nanomaterials (MBNs) as multifunctional platforms for next‐generation diagnostics and nanodynamic therapies (NDTs), highlighting their structural tunability, diverse therapeutic modalities, and broad biomedical applications in oncology and infectious disease control.
Qihang Ding, Wenhao Li, Ling Mei, Suling Luo, Jing Tao, Chongxiu Shi, Hongping Yang, Wei Feng, Yungchang Chen, Yu Chen, Jong Seung Kim, Xue Shen   +11 more
wiley   +1 more source

Hif-1 responsive IFFLs to explain specific transcriptional responses to cycling hypoxia in cancers. [PDF]

NPJ Syst Biol Appl
Qiu X, Liu Y, Vera-Licona P, Agmon E, Kshitiz, Suhail Y.   +5 more
europepmc   +1 more source

An oxidative DNA “damage” and repair mechanism localized in the VEGF promoter is important for hypoxia-induced VEGF mRNA expression [PDF]

, 2015
Viktor Pastukh, Justin T. Roberts, David W. Clark, Gina C. Bardwell, Mita Patel, Abu‐Bakr Al‐Mehdi, Glen M. Borchert, Mark N. Gillespie   +7 more
openalex   +1 more source

Mitochondria‐Targeted Nanomotor: H2S‐Driven Cascade Therapy for Hepatocellular Carcinoma

Advanced Materials, EarlyView.
A mitochondrial‐targeted nanomotor integrates photodynamic therapy, mild photothermal therapy, and enzyme dynamic therapy into a self‐amplifying cascade through H2S‐driven metabolic reprogramming. Abstract Despite advances in combination therapies for cancer treatment, most strategies rely on modular‐additive designs that lack dynamic molecular cues to
Chengcheng Li, Xiaodong Ma, Shiji Fang, Biao Chen, Xinru Wang, Lingyun He, Xin Yang, Yuanqiang Li, Jessica M. Rosenholm, Zhongwei Zhao, Jiansong Ji, Hongbo Zhang   +11 more
wiley   +1 more source

Alterations in the gastric and small intestinal microbiota of mice exposed to short-term and long-term hypoxia. [PDF]

Sci Rep
Liao X, Wang X, Wang X, Zhang M, Ren F, Wang D, Sheng J.   +6 more
europepmc   +1 more source