Results 211 to 220 of about 927,905 (356)

Recent Advances in Robotic Systems for Robot‐Assisted Transoral Surgical Procedures: A Systematic Review

open access: yesAdvanced Robotics Research, EarlyView.
This review systematically examines robotic systems for robot‐assisted transoral surgical procedures, classifying them based on transoral access depth, and evaluates their fundamental design principles, mechanical innovations, algorithmic advancements, and clinical implementation status.
Yuhao Shi   +5 more
wiley   +1 more source

Tumour Hypoxia [PDF]

open access: yesClinical Oncology, 2019
C.M. West, F. Slevin
openaire   +2 more sources

XBP1s Mediates Cross‐resistance to Combination Treatment of CDK4/6 Inhibitors plus Endocrine Therapy in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Elevated spliced form of X‐box–binding protein 1 (XBP1) correlates with unfavorable responses to endocrine therapy plus CDK4/6 inhibitors in HR+/HER2− advanced breast cancer. XBP1s facilitates cell proliferation and G1/S transition by transcriptionally activating SND1, thereby activating the E2F1 pathway.
Yuting Sang   +11 more
wiley   +1 more source

Branched‐Chain α Keto‐Acid Dehydrogenase Kinase‐Mediated AKT Phosphorylation Promotes RCC Tumorigenesis and Drug Resistance

open access: yesAdvanced Science, EarlyView.
This study identifies a novel oncogenic role and a previously unrecognized phosphorylation substrate of BCKDK in RCC, wherein it promotes tumor progression and drug resistance through AKT phosphorylation at both Thr308 and Ser473 sites and activation of AKT/mTOR and AKT/ABCB1 signaling pathways, offering a promising prognostic marker and therapeutic ...
Qin Tian   +18 more
wiley   +1 more source

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