Results 211 to 220 of about 939,686 (311)

FOXD1, a hypoxia-related gene, accelerates prostate cancer cell growth by increasing glycolysis under hypoxia conditions. [PDF]

BMC Biotechnol
Gao J, Wu S.
europepmc   +1 more source

Laser Ultrasound Super‐Resolution Imaging for Multi‐Parametric Non‐Invasive Volumetric Characterization of Brain Cancer

Advanced Science, EarlyView.
Laser ultrasound super‐resolution imaging (LUSSI) leverages laser‐generated ultrasound for functional 3D transcranial imaging of brain tumor vasculature. Combined with optoacoustic tomography, it is demonstrated in a glioblastoma model, revealing structural abnormalities, compressed vessels, hemorrhages, and hypoxic regions.
Daniil Nozdriukhin, Yi Chen, Shuxin Lyu, Daniel Razansky, Xosé Luís Deán‐Ben   +4 more
wiley   +1 more source

Anle138b mitigates post-hypoxic cognitive impairment, α-Synuclein aggregation and UPR activation in Drosophila melanogaster. [PDF]

Acta Neuropathol Commun
Fehr AT, Jung J, Kokott-Vuong A, Sahnoun SEM, Ezzat AA, Huber M, Bliss TM, Voigt A, Schulz JB, Habib P.   +9 more
europepmc   +1 more source

Sc(III) Complexes of Pyclen Derivative Ligands as Probes for Hypoxia: Synthesis, Chemical Characterization, ⁴⁴ Sc‐Radiolabeling, and Preclinical Assessment [PDF]

Tibor Csupász, Bayar Dahman, Tamás Gyula Gál, Istvan Kapus, Zita Képes, Dániel Szücs, György Trencsényi, Imre Tóth, Anikó Fekete, Gyula Tircso, Tibor Csupász, Bayar Dahman, Tamás Gyula Gál, Istvan Kapus, Zita Képes, Dániel Szücs, György Trencsényi, Imre Tóth, Anikó Fekete, Gyula Tircso   +19 more
openalex   +1 more source

Methanotrophs are favored under hypoxia in ammonium-fertilized soils [PDF]

, 2018
Anna Walkiewicz, Małgorzata Brzezińska, Andrzej Bieganowski   +2 more
openalex   +1 more source

Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma

Advanced Science, EarlyView.
IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang, Hua Yang, Yifan Yuan, Chenyang Zhang, Ziwei Fu, Yanyan Chen, Yinghong Xiong, Shuyu Chen, Kexin Ling, Ying Liu, Jason T. Huse, Bo Chen, Timothy A. Chan, Zengxin Qi, Zhao Zhang, Xiuping Liu, Yuxiang Wang   +16 more
wiley   +1 more source

Effects of Intermittent Hypoxia Protocols on Physical Performance in Trained and Untrained Individuals: An Umbrella Review of Systematic Reviews and Meta-Analyses. [PDF]

Sports Med Open
Boulares A, Dupuy O, Bragazzi NL, Pichon A.   +3 more
europepmc   +1 more source

Adamts1 Exacerbates Post‐Myocardial Infarction Scar Formation via Mechanosensing of Integrin α8

Advanced Science, EarlyView.
Proposed mechanistic model of ADAMTS1‐ITGα8 mechanotransduction in post‐MI scar formation. Schematic illustration showing the mechanistic pathway by which endothelial cell (EC) derived Adamts1 regulates cardiac fibroblast activation through ITGα8‐mediated mechanotransduction following myocardial infarction (MI).
Chun‐Yan Kong, Zhen Guo, Yu‐Lan Ma, Ming‐Yu Wang, Hai‐Yang Ni, Pan Wang, Wen‐Jun Qiu, En‐Gui Wang, Zhou Li, Zheng Yang, Bo Shen, Qi‐Zhu Tang   +11 more
wiley   +1 more source

Role of P2X7 Receptor on Hypoxia-Induced Vascular Endothelial Growth Factor Gene Expression in H9c2 Rat Cardiomyocytes. [PDF]

J Cardiovasc Dev Dis
Bin Dayel AF, Alhejji RM, Alonazi AS, Alrasheed NM.   +3 more
europepmc   +1 more source

A Hypoxia‐Responsive Single‐Atom Sonozyme for Targeted Sonocatalytic Therapy in Alleviating Atherosclerotic Plaque

Advanced Science, EarlyView.
A tetranitrogen‐coordinated single‐atom manganese catalyst (SMC) is fabricated with outstanding sonosensitization efficiency and multi‐enzyme‐like catalytic properties. To enable better targeting of M1 macrophages, hyaluronic acid (HA) is applied to modify the surface of SMC, yielding SMC‐HA nanozymes.
Qiaofei Chen, Guotao Yuan, Zhiwen Liu, Zhengyu Cao, Li He, Ruonan Li, Tongsheng Huang, Minglong Zheng, Kexin Wen, Canxia Huang, Shuang Zhu, Pingyu Zhang, Jingfeng Wang, Yuling Zhang, Yue Pan   +14 more
wiley   +1 more source