Results 311 to 320 of about 1,114,410 (399)

Erythropoietin‐Stimulated Macrophage‐Derived Extracellular Vesicles in Chitosan Hydrogel Rescue BMSCs Fate by Targeting EGFR to Alleviate Inflammatory Bone Loss in Periodontitis

Advanced Science, EarlyView.
A therapeutic strategy is proposed for periodontitis using extracellular vesicles derived from EPO‐stimulated macrophages (EPO‐EVs). This schema demonstrates how EPO‐EVs enhance the osteogenic activity of mBMSCs in an inflammatory environment by inhibiting EGFR.
Shuchen Liu, Zhuoran Wang, Yuhuan Li, Ziyi Pan, Lei Huang, Jing Cui, Xue Zhang, Mingxi Yang, Yuan Zhang, Daowei Li, Hongchen Sun   +10 more
wiley   +1 more source

Impact of m6A modification and transcript quantity on mRNA composition in plant stress granules under hypoxia. [PDF]

J Exp Bot
Kubiak DJ, Szcześniak MW, Ostrowska K, Bielewicz D, Bhat SS, Niedojadło K, Szweykowska-Kulińska Z, Jarmołowski A, Fray RG, Niedojadło J.   +9 more
europepmc   +1 more source

Studies on the Cardiopulmonary Function in Tuberculosis 1. : Effects of Hypoxia on Cardiopulmonary Functions in Patients with Pulmonary Tuberculosis.

, 1960
Mikio Kato
openalex   +2 more sources

Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury

Advanced Science, EarlyView.
Dipyridamole acts as a clinically used compound to suppress ferroptosis. Dipyridamole down‐regulates the expression of RNF126, which is an E3 ligase to ubiquitinate SLC7A11 for proteasome degradation. The deficiency of SLC7A11 largely abolishes the protective role of dipyridamole both in vitro and in vivo.
Xiao Zhuang, Shuang Shi, Shuo Liu, Yaqiong Jiao, Bin Huang, Yinghong Yang, Li Yang, Xinquan Yang, Hui Wang, Chunhui Liang, Dandan Song, Huaxiang Yu, Dan Zou, Qi Sun, Shu Yang, Chengqian Yin, Jian Li, Yiming Liu, Junxia Min, Fudi Wang, Yong Nian, Lutao Du, Bo Chu   +22 more
wiley   +1 more source

3D‐Printed Titanium Trabecular Scaffolds with Sustained Release of Hypoxia‐Induced Exosomes for Dual‐Mimetic Bone Regeneration

Advanced Science, EarlyView.
This study presents 3D‐printed Ti‐6Al‐4V trabecular scaffolds combined with hypoxia‐induced exosomes encapsulated in PEGDA/GelMA microspheres for sustained release. The scaffolds mimic the structure of natural bone, while the exosome delivery system enhances osteogenesis and angiogenesis, significantly promoting bone regeneration and offering a ...
Lincong Luo, Weihan Zheng, Jiaying Li, Tingting Chen, Wanting Xue, Tao Lin, Mingrui Liu, Zi Yan, Jiaxin Yang, Jiamin Li, Jiahao Pu, Yaobin Wu, Konghe Hu, Shiyu Li, Wenhua Huang   +14 more
wiley   +1 more source

Hypoxic HPV-Positive Cancer Cells Are Particularly Sensitive to the Pro-Senescent Effects of B-MYB Repression Due to the Lack of Compensatory A-MYB Induction. [PDF]

J Med Virol
Velimirović M, Avenhaus A, Lohrey C, Bulkescher J, Hoppe-Seyler F, Hoppe-Seyler K.   +5 more
europepmc   +1 more source

An Intelligent and Conductive Hydrogel with Multiresponsive and ROS Scavenging Properties for Infection Prevention and Anti‐Inflammatory Treatment Assisted by Electrical Stimulation for Diabetic Wound

Advanced Science, EarlyView.
This study introduces a novel therapeutic approach that employs a conductive hydrogel (HEPP) responsive to near‐infrared light, pH levels, and reactive oxygen species. Its goal is to enhance the healing environment affected by elevated glucose levels, insufficient oxygen, and bacterial infections in diabetes‐related wounds.
Tao Zhang, Zongwu Meng, Haoyu Yu, Ping Ding, Tianhan Kai   +4 more
wiley   +1 more source

Utility of the Respiratory Compensation Point for Estimating Critical Power: Insights From Normoxia and Hypoxia. [PDF]

Eur J Sport Sci
Marwood S, Parker Simpson L, Wilkerson DP, Jones AM, Goulding RP.   +4 more
europepmc   +1 more source

Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization

Advanced Science, EarlyView.
This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim, Hyeok Kim, Dong‐Hyun Lee, Yeong Hwan Kim, Jae‐Hyun Park, Woo‐Sup Sim, Jin‐Ju Kim, Kiwon Ban, Soong Ho Um, Hyun Ji Park, Michael E. Davis, Hun‐Jun Park, Suk Ho Bhang   +12 more
wiley   +1 more source