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Statement of Retraction: Knockdown of hypoxia-inducible factor 1-alpha (HIF1α) interferes with angiopoietin-like protein 2 (ANGPTL2) to attenuate high glucose-triggered hypoxia/reoxygenation injury in cardiomyocytes. [PDF]
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Conquering the Hypoxia Limitation for Photodynamic Therapy
Advanced Materials, 2021Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity.
Jing Lin, Lian-hua Fu, Peng Huang
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Cellular adaptation to hypoxia through hypoxia inducible factors and beyond
Nature Reviews Molecular Cell Biology, 2020 Pearl Lee +2 more
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Hypoxia — a key regulatory factor in tumour growth
Nature Reviews Cancer, 2002Adrian L Harris
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Targeting hypoxia in cancer therapy
Nature Reviews Cancer, 2011William R Wilson, Michael P Hay
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Hypoxia-Modified Cancer Cell Metabolism
Frontiers in Cell and Developmental Biology, 2019 While oxygen is critical to the continued existence of complex organisms, extreme levels of oxygen within a system, known as hypoxia (low levels of oxygen) and hyperoxia (excessive levels of oxygen), potentially promote stress within a defined biological
Tina P Dale, Nicholas R Forsyth
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Hypoxia Imaging As a Guide for Hypoxia-Modulated and Hypoxia-Activated Therapy
Antioxidants & Redox Signaling, 2022Significance: Oxygen imaging techniques, which can probe the spatiotemporal heterogeneity of tumor oxygenation, could be of significant clinical utility in radiation treatment planning and in evaluating the effectiveness of hypoxia-activated prodrugs. To fulfill these goals, oxygen imaging techniques should be noninvasive, quantitative, and capable of ...
Jeffrey R. Brender +4 more
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Hypoxia. 5. Hypoxia and hematopoiesis
American Journal of Physiology-Cell Physiology, 2011Our understanding of organismal responses to hypoxia has stemmed from studies of erythropoietin regulation by hypoxia that led to the discovery of the master regulator of the hypoxic response, i.e., hypoxia-inducible factor (HIF). This is a transcription factor that is now known to induce the expression of a battery of genes in response to hypoxia ...
Donghoon Yoon +2 more
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