Results 211 to 220 of about 97,129 (264)

A Fully-Automated Environmental Chamber for Examination of Long-Term Effects of Intermittent Hypoxia on Medium-Size Animals.

, 1999
Xavier OHAUFOUR, Faiq G. Issa, Colin E. Sullivan, Craig S. McLachlan, Gunnar Unger   +4 more
openalex   +2 more sources

Chronic ER Stress Triggers Cell‐Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia

Advanced Science, EarlyView.
Acute myeloid leukemia (AML) remains a therapeutic challenge due to its heterogeneity and limited targets. Here, multi‐omics analyses are utilized, and it is revealed that AML cells, particularly the FLT3‐ITD+ subtype, undergo chaperone‐mediated ER stress, inducing surface translocation of ER chaperones.
Yimin Zhou, Zhenfei Zhong, Peng Hu, Weigang Wang, Ying Song, Na Yang, Fangyan He, Yajie Li, Qi Sa, Yanmei Yang, Qinmiao Sun, Tonghua Yang, Beibei Zhang, Dahua Chen   +13 more
wiley   +1 more source

DISBAC₂(3) fluorescent probes illuminate new paths for screening stress-resistant crops. [PDF]

Plant Physiol
Shi T, Zhang J, Zhang N.
europepmc   +1 more source

Widespread reproductive disruption, masculinization and endocrine imbalance in croaker exposed to environmental hypoxia

, 2011
Rahman Md. Saydur
openalex   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Identification of Quantitative Trait Loci and Candidate Genes Involved in Rice Seedling Growth Under Hypoxic Stress. [PDF]

Int J Mol Sci
Kim N, Jan R, Asif S, Asaf S, Khan Z, Kim KM.   +5 more
europepmc   +1 more source

Punicalagin Enhances Autophagy Through Sirtuin 1/FoxO3a Axis to Inhibit Intracellular Mycobacterium Abscessus Infection

Advanced Science, EarlyView.
Punicalagin, a pomegranate molecule, helps the body fight Mycobacterium abscessus. It preferentially boosts interstitial macrophages in the lung, stabilizing mitochondria and switching on the autophagy via SIRT1/FoxO3a, which lowers bacterial load without directly killing bacteria.
Kefan Bi, Bihan Xu, Dan Cao, Kaijin Xu, Ying Zhang   +4 more
wiley   +1 more source

Cardiac and ventilatory responses of rainbow trout (Salmo gairdneri) to environmental hypoxia and hypercapnea

, 2010
Frank Melvin Smith
openalex   +1 more source

Smoking‐Induced STC2+ Tumor Cells Drive Tumor‐Vascular Crosstalk in Laryngeal Squamous Cell Carcinoma via Spatial and Single‐Cell Transcriptomics

Advanced Science, EarlyView.
This study identifies a smoking‐induced mechanism in LSCC whereby nicotine activates the CHRNA5–JAK2/STAT3 axis to drive STC2 transcription. STC2 upregulates TGFBI, which interacts with endothelial ITGA5 to regulate vascular permeability and promote metastasis.
Yujie Shen, Lianchong Gao, Qiang Huang, Liang Zhou, Chengzhi Xu, Chunping Wu   +5 more
wiley   +1 more source

Necrotic and apoptotic adipocytes in the hypoxic tumor microenvironment supply triglycerides to induce cisplatin resistance in the metastatic lymph nodes of head and neck carcinoma. [PDF]

Cell Death Dis
Li F, Huang H, Huang Q, Mao X, Cong N, Zhuang W, Hsueh CY, Zhang M.   +7 more
europepmc   +1 more source