Results 71 to 80 of about 4,650,121 (384)

Hypoxia as an Environmental Cause of Holoprosencephaly

open access: yesThe FASEB Journal, 2009
Holoprosencephaly is a complex congenital malformation of the forebrain and face. Recent clinical evidence shows a correlation between hypoxia and holoprosencephaly. We examined the role of hypoxia in causing holoprosencephaly in chick embryos.
Francis Joel Smith, Ralph S Marcucio
openaire   +1 more source

An Aptitude for Altitude: Are Epigenomic Processes Involved?

open access: yesFrontiers in Physiology, 2019
In recent years, high-throughput genomic technologies and computational advancements have invigorated efforts to identify the molecular mechanisms regulating human adaptation to high altitude. Although exceptional progress regarding the identification of
Colleen G. Julian
doaj   +1 more source

Hypoxic Culture Conditions as a Solution for Mesenchymal Stem Cell Based Regenerative Therapy [PDF]

open access: yes, 2014
Cell-based regenerative therapies, based on in vitro propagation of stem cells, offer tremendous hope to many individuals suffering from degenerative diseases that were previously deemed untreatable.
Abu Kasim, N. H.   +3 more
core   +1 more source

Glial response to hypoxia in mutants of NPAS1/3 homolog Trachealess through Wg signaling to modulate synaptic bouton organization.

open access: yesPLoS Genetics, 2019
Synaptic structure and activity are sensitive to environmental alterations. Modulation of synaptic morphology and function is often induced by signals from glia. However, the process by which glia mediate synaptic responses to environmental perturbations
Pei-Yi Chen   +4 more
doaj   +1 more source

Interactions between oxygen homeostasis, food availability, and hydrogen sulfide signaling

open access: yesFrontiers in Genetics, 2012
The ability to sense and respond to stressful conditions is essential to maintain organismal homeostasis. It has long been recognized that stress response factors that improve survival in changing conditions can also influence longevity.
Nicole N Iranon   +2 more
doaj   +1 more source

Polycyclic Aromatic Hydrocarbons Have Adverse Effects on Benthic Communities in the Baltic Sea: Implications for Environmental Status Assessment

open access: yesFrontiers in Environmental Science, 2021
Changes in benthic macrofaunal communities are indicative of environmental stressors, including eutrophication and hypoxia. However, some species are sensitive not only to hypoxia but also to various environmental contaminants.
Caroline Raymond   +3 more
doaj   +1 more source

Ionoregulatory Aspects of the Osmorespiratory Compromise during Acute Environmental Hypoxia in 12 Tropical and Temperate Teleosts

open access: greenPhysiological and Biochemical Zoology, 2015
Lisa Robertson   +3 more
openalex   +3 more sources

Hypoxia diminishes the detoxification of the environmental mutagen benzo[a]pyrene [PDF]

open access: yesMutagenesis, 2014
Hypoxia promotes genetic instability and is therefore an important factor in carcinogenesis. We have previously shown that activation of the hypoxia responsive transcription factor HIFα can enhance the mutagenic phenotype induced by the environmental mutagen benzo[a]pyrene (BaP).
Schults, M.A.C.   +5 more
openaire   +3 more sources

Differential Expression of miRNAs in the Respiratory Tree of the Sea Cucumber Apostichopus japonicus Under Hypoxia Stress

open access: yesG3: Genes, Genomes, Genetics, 2017
The sea cucumber, an important economic species, has encountered high mortality since 2013 in northern China because of seasonal environmental stress such as hypoxia, high temperature, and low salinity. MicroRNAs (miRNAs) are important in regulating gene
Da Huo   +7 more
doaj   +1 more source

Hot and hypoxic environments inhibit simulated soccer performance and exacerbate performance decrements when combined. [PDF]

open access: yes, 2016
The effects of heat and/or hypoxia have been well-documented in match-play data. However, large match-to-match variation for key physical performance measures makes environmental inferences difficult to ascertain from soccer match-play.
Abt   +65 more
core   +5 more sources

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