Results 91 to 100 of about 25,541 (250)

Neuroprotective effects of ginsenoside Rg1-induced neural stem cell transplantation on hypoxic-ischemic encephalopathy

Neural Regeneration Research, 2015
Ginsenoside Rg1 is the major pharmacologically active component of ginseng, and is reported to have various therapeutic actions. To determine whether it induces the differentiation of neural stem cells, and whether neural stem cell transplantation after ...
Ying-bo Li, Yan Wang, Ji-ping Tang, Di Chen, Sha-li Wang   +4 more
doaj   +1 more source

Early Prediction of Outcome Using Lactate Dehydrogenase and Amplitude‐Integrated EEG in Transported Newborn Infants with Hypoxic–Ischaemic Encephalopathy

Acta Paediatrica, EarlyView.
ABSTRACT Aim To investigate whether early lactate dehydrogenase (LDH) and amplitude‐integrated electroencephalography (aEEG) improve the prediction of outcome in outborn infants transported for therapeutic hypothermia. Method Secondary analysis of a randomised controlled trial (2016–2019) including 113 asphyxiated newborn infants randomised to ...
Hang T. T. Tran, Ha T. Le, Dien M. Tran, Tobias Alfvén, Linus Olson, Lena Hellstrom‐Westas   +5 more
wiley   +1 more source

Mortality in patients with hypoxic ischemic encephalopathy treated with therapeutic hypothermia

Purpose: Hypoxic-ischemic encephalopathy is a heterogeneous clinical syndrome that occurs in the perinatal period and is characterized by altered consciousness or seizures, respiratory depression, and hypotension.
Tunc, Gaffari, Mutlu, Muhammet Ali, Korgali, Elif Unver, Gulturk, Esra Akaydin, Unsal, Gulsah   +4 more
core   +1 more source

Role of Matrix Metalloproteinase-9 in Neonatal Hypoxic-Ischemic Encephalopathy

, 2019
BACKGROUND: Neonatal encephalopathy is a heterogeneous syndrome characterised by signs of central nervous system dysfunction in the newborn. Matrix metalloproteinase-9(MMP-9) increases the blood-brain barrier permeability, and their inhibitors can reduce
Salah, Mohab M., Abdelmawla, MA, Eid, Sally R., hasanin, rasha mahmoud, Mostafa, Eman A., Abdelhameed, MW   +5 more
core   +1 more source

Intracranial hemorrhage identified after initiating therapeutic hypothermia: two case reports of neonatal hypoxic-ischemic encephalopathy due to hypovolemic shock with anemia: a case report

Journal of Medical Case Reports
Background Therapeutic hypothermia for moderate-to-severe hypoxic-ischemic encephalopathy in neonates effectively improves neurological outcomes when initiated within 6 hours of birth.
Takatoshi Murakami, Kenichi Tanaka, Ryousuke Sasaki, Shirou Matsumoto, Kimitoshi Nakamura   +4 more
doaj   +1 more source

Elevated Serum Neurofilament Light Chain Is Associated With Systemic Inflammation in Very Preterm Infants

Acta Paediatrica, EarlyView.
ABSTRACT Aim Neurofilament light chain (NFL) and glial fibrillary acidic protein (GFAP) are known biomarkers of brain injury in adults, but their significance in very preterm (VPT) infants remains unclear. Given the strong link between inflammation, oxidative stress, and brain injury in this population, we investigated associations between NFL, GFAP ...
E.‐V. Kivivuori, S.‐K. Herukka, S. Kärkkäinen, T. Kokkola, J. Kirjavainen, U. Sankilampi   +5 more
wiley   +1 more source

Why hypothermia in neonatal hypoxic ischemic encephalopathy?

, 2001
Gucuyener K, Ergenekon E. Why hypothermia in neonatal hypoxic ischemic encephalopathy!
Ergenekon, E, Gucuyener, K
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Structural changes in model of hypoxic-ischemic encephalopathy in rat [PDF]

, 2019
Title: Structural changes in model of hypoxic-ischemic encephalopathy in rat Objectives: The aim of the research is to develop a model of hypoxic-ischemic encephalopathy in a rat that would represent perinatal injury in a human and then histologically ...
Slotta, Michal
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German Hypothermia Registry Improves Clinician Confidence and Harmonises Decentralised Neonatal Hypoxic‐Ischaemic Encephalopathy Care in Germany

Acta Paediatrica, EarlyView.
ABSTRACT Aim Decentralised implementation of therapeutic hypothermia (TH) for neonatal hypoxic‐ischaemic encephalopathy (HIE) in Germany historically caused heterogeneous clinical practices. The aim of this study was to assess the impact of the German Hypothermia Registry on clinical standardisation and confidence in neonatal HIE care since its ...
Till Dresbach, Khaled Abdelrahman, Sebiha Demir, Anne Groteklaes, Alexandra Boeckenhoff, Andreas Mueller, Hemmen Sabir, on behalf of the German Hypothermia Registry, Milian Brasche, Nicolas Allgaier, Daniel Klotz, Norbert Teig, Katja Schneider, Hemmen Sabir, Sandra Holz, Birte Tröger, Thorsten Körner, Uwe Höpner, Marie Schmenk, Michael Hofmann, Mario Rüdiger, Julia Osterholt, Martin Berghäuser, Christopher Willerscheidt, Farina Morgenroth, Hans Jörg Bittrich, Steven Hébert, Arber Arapi, Anja Stein, Veit Lange, Gunnar Rau, Nikolas Hillenbrandt, Matthias Reger, Susanne Schade, Jana Dieks, Heimke von Osten, Marita Horstkemper, Martin Blohm, Mario Lange, Bettina Bohnhorst, Simon Kranig, Maurice Petrasch, Nasenien Nourkami‐Tutdibi, Christiane Pinkwart, Thomas Kriebel, Julia Jerabek, Nora Bonney, Angela Kribs, Clemens Andrée, Sophia Stadermann, Kirsten Glaser, Peter Jahn, Katrin Braun, Anna Eisenhardt, Alba Perez‐Ortiz, Nadine Mand, Timea Takacs, Anja Jäger, Oliver Schroers, Esther Schouten, Claudia Nussbaum, Kai Böckenholt, Rüdiger Wentzell, Guido Engelmann, Katherine Louise Kastor, Michael Schroth, Matthias Engler, Friederike Eichhorn, Moritz Rohrbach, Fabian Bärtling, Frank Dohle, Matthias Keller, Marion Weber, Verena Lehnerer, Anja Mayer, Marie‐Claire Detemple, Valentin Oellers, Markus Pingel, Friederike Eilbracht, Jutta Adler, Elena Eberle, Karoline Goj, Virginia Toth, Andrea Czoske, Cornelia Wiechers, Christiane Mayer, Anja Schumann, Patrick Salaschek, Janaina Rauch, Kai Hensel, Pia Paul   +90 more
wiley   +1 more source

Brain Diffusivity in Infants With Hypoxic-Ischemic Encephalopathy Following Whole Body Hypothermia: Preliminary Results [PDF]

, 2020
Hypoxic-ischemic encephalopathy is an important cause of neuropsychological deficits. Little is known about brain diffusivity in these infants following cooling and its potential in predicting outcome. Diffusion tensor imaging was applied to 3 groups: (1)
MD Irit Berger, PhD Ronny Geva, MD Liat Ben Sira, MD Yakov Shiff, MD Haim Bassan, MD Varda Gross-Tsur, MD Yoram Bental, MSc Moran Artzi, PhD Dafna Ben Bashat, MD Yael Leitner, MSc Maya Weinstein, MD Ronella Marom   +11 more
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