Results 91 to 100 of about 34,963 (242)

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

Med Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang, Yuying Mo, Zhishan Ling, Yuting Zeng, Qi Zhang, Shuqi Zheng, Shuyang Wen, Yupeng Xiao, Siying Long, Tingting Yang, Qianru Li, Wenjie Shi, Guozhi Huang, Qing Zeng   +13 more
wiley   +1 more source

Efficacy of passive hypothermia and adverse events during transport of asphyxiated newborns according to the severity of hypoxic-ischemic encephalopathy

Jornal de Pediatria, 2018
Objective: To determine if the efficacy of passive hypothermia and adverse events during transport are related to the severity of neonatal hypoxic-ischemic encephalopathy.
Nuria Carreras, Miguel Alsina, Ana Alarcon, Gemma Arca-Díaz, Thais Agut, Alfredo García-Alix   +5 more
doaj   +3 more sources

Brain injury due to persistent hyperinsulinemic hypoglycemia of infancy [PDF]

, 2007
A
De Visschere, Pieter, Senepart, Maarten, Seynaeve, Patrick, Vanrietvelde, Frederik   +3 more
core   +2 more sources

Characterising Forces Applied During the Simulated Management of Impacted Fetal Head: Pre‐Clinical Methods Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Evaluate whether a sensorised surgical glove can serve as an effective training tool in management of impacted fetal head; and improvements needed. Examine location and amount of force applied through operators' hands during simulated disimpaction. Design Feasibility study.
Dawn Parris, Yang Xue, Thurga Navaseelan, Carmen Salvadores Fernandez, Maryam Javidan, Rohit Gupta, Nikolaos Salaris, Jeremy Chen, Manish K. Tiwari, Dimitrios Siassakos   +9 more
wiley   +1 more source

Predictive Value of Early A-EEG in HIE Outcome

Pediatric Neurology Briefs, 2011
Researchers at Wayne State University and other US Pediatric Centers examined the predictive value of the early amplitude integrated electroencephalogram (aEEG) and stage of encephalopathy among infants with hypoxic-ischemic encephalopathy (HIE) eligible
J Gordon Millichap
doaj   +1 more source

The Performance of Selective Screening Ultrasound to Detect the Small‐for‐Gestational‐Age Foetus: A Prospective Cohort Study Nested Within the DESiGN Randomised Control Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Evidence on the performance of foetal growth ultrasound parameters to detect the Small‐for‐Gestational‐Age (SGA) foetus for a selective cohort is limited. We report the performance of estimated foetal weight under the 10th percentile (EFW < 10th) at the last selective screening ultrasound to detect SGA based on gestational age of ...
Charles Arcus, James Elhindi, Chivon Winsloe, Andrew Copas, Sophie Relph, Annette Briley, Kirstie Coxon, Mark Johnson, Asma Khalil, Deborah A. Lawlor, Christoph Lees, Neil Marlow, Louise Page, Andrew Shennan, Jane Sandall, Tanya Nippita, Matias C. Vieira, Dharmintra Pasupathy   +17 more
wiley   +1 more source

MRI in Hypoxic-Ischemic Encephalopathy

Pediatric Neurology Briefs, 2012
Researchers at University of Melbourne, Australia, and St Louis Children’s Hospital, US investigated the effects of hypothermia treatment on MRI patterns of brain injury in newborns with hypoxic-ischemic encephalopathy (HIE) and the prognostic utility of
J Gordon Millichap
doaj   +1 more source

Correlation of Thompson Score in Predicting Early Outcome of Newborn with Birth Asphyxia

Journal of Nepal Health Research Council, 2020
Background: Birth asphyxia is one of the important causes of neonatal morbidity and mortality, accounting up to 30% of neonatal death in Nepal. It is also an important cause of long term neurological disability and impairment.
Sabina Shrestha, Sangita Puree Dhungana, Sujit Shrestha, Gentle Sunder Shrestha   +3 more
doaj   +1 more source

Outcomes of safety and effectiveness in a multicenter randomized, controlled trial of whole-body hypothermia for neonatal hypoxic-ischemic encephalopathy. [PDF]

, 2008
BACKGROUND: Whole-body hypothermia reduced the frequency of death or moderate/severe disabilities in neonates with hypoxic-ischemic encephalopathy in a randomized, controlled multicenter trial.
Das, Abhik, Ehrenkranz, Richard A., Goldberg, Ronald N., Higgins, Rosemary D., Laptook, Abbott R., McDonald, Scott A., Network, NICHD Neonatal Research, Pappas, Athina, Shankaran, Seetha, Tyson, Jon E., Walsh, Michelle   +10 more
core   +1 more source

Neuropathologic findings and age‐related differences in Finnish pediatric medico‐legal autopsies

Journal of Forensic Sciences, EarlyView.
Abstract Neuropathological examination plays a critical role in medico‐legal cause‐of‐death investigation, especially in determining the cause and manner of death in pediatric autopsies. Although a comprehensive neuropathological examination is recommended, limited data exists of the diagnostic yield of neuropathology consultations in such cases.
Elias Hakanen, Petteri Oura, Paula Katriina Vauhkonen   +2 more
wiley   +1 more source