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Acute high-altitude illness: risk factors, susceptibility prediction, and personalized prevention and treatment. [PDF]

open access: yesFront Med (Lausanne)
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Hypoxic pulmonary vasoconstriction

General Pharmacology: The Vascular System, 1999
Hypoxic vasoconstriction is unique to pulmonary circulation. The pulmonary response is part of a self-regulatory mechanism by which pulmonary capillary blood flow is automatically adjusted to alveolar ventilation for maintaining the optimal balance of ventilation and perfusion. In pathological conditions, hypoxic pulmonary vasoconstriction may occur as
J P, Dumas   +3 more
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Hypoxic pulmonary vasoconstriction

Journal of Applied Physiology, 2005
Humans encounter hypoxia throughout their lives. This occurs by destiny in utero, through disease, and by desire, in our quest for altitude. Hypoxic pulmonary vasoconstriction (HPV) is a widely conserved, homeostatic, vasomotor response of resistance pulmonary arteries to alveolar hypoxia.
Rohit, Moudgil   +2 more
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Hypoxic Pulmonary Vasoconstriction

High Altitude Medicine & Biology, 2013
Hypoxic pulmonary vasoconstriction (HPV) continues to fascinate cardiopulmonary physiologists and clinicians since its definitive description in 1946. Hypoxic vasoconstriction exists in all vertebrate gas exchanging organs. This fundamental response of the pulmonary vasculature in air breathing animals has relevance to successful fetal transition to ...
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Hypoxic pulmonary vasoconstriction

Essays in Biochemistry, 2007
HPV (hypoxic pulmonary vasoconstriction) is the critical and distinguishing characteristic of the arteries that feed the lung. In marked contrast, systemic arteries dilate in response to hypoxia to meet the metabolic demands of the tissues they supply.
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[Hypoxic pulmonary vasoconstriction].

Der Anaesthesist, 1996
Hypoxic pulmonary vasoconstriction (HPV) was first described by von Euler and Liljestrand in 1946 and is still the only known vascular feedback control mechanism in the lung. This technique results in a redistribution of blood flow away from poorly ventilated areas into better ventilated regions, thus reducing shunt.
I L, Theissen, A, Meissner
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Hypoxic Pulmonary Vasoconstriction

Anesthesiology, 2015
AbstractAbstract Hypoxic pulmonary vasoconstriction (HPV) represents a fundamental difference between the pulmonary and systemic circulations. HPV is active in utero, reducing pulmonary blood flow, and in adults helps to match regional ventilation and perfusion although it has little effect in healthy lungs.
Andrew B, Lumb, Peter, Slinger
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Hypoxic pulmonary vasoconstriction in chronically hypoxic rats

Respiration Physiology, 1984
Reactivity of lung vessels to acute hypoxia was found increased or decreased in chronically hypoxic (CH) rats by different authors. We examined severity and duration of hypoxia and age as possible explanations. Isolated blood-perfused lungs of CH rats ventilated with low-O2 mixtures were compared with control (C) rats. Juvenile CH rats (10 or 12% O2, 3
D, Bee, R A, Wach
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