Results 181 to 190 of about 12,758 (223)

Alveolar mechanics alter hypoxic pulmonary vasoconstriction*

Critical Care Medicine, 2002
Hypoxic pulmonary vasoconstriction is the primary physiologic mechanism that maintains a proper ventilation/perfusion match, but it fails in diffuse lung injuries such as acute respiratory distress syndrome. Acute respiratory distress syndrome is associated with pulmonary surfactant loss that alters alveolar mechanics (i.e., dynamic change in alveolar ...
Ulysse G, McCann, Henry J, Schiller, Louis A, Gatto, Jay M, Steinberg, David E, Carney, Gary F, Nieman   +5 more
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Naloxone: Effects on hypoxic pulmonary vasoconstriction

Annals of Emergency Medicine, 1984
To determine the effect of naloxone on the hypoxic pulmonary vasoconstrictive response, six mongrel dogs were rendered hypoxic with 10% oxygen and were given either saline or naloxone. Following hypoxia all dogs had significant increases in mean pulmonary artery pressure (PAP) and pulmonary arterial resistance index (PARI) without changes in cardiac ...
D, Bar-Or, J T, Good, J A, Marx, E E, Moore, J V, Winkler   +4 more
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Ritodrine inhibition of hypoxic pulmonary vasoconstriction

American Journal of Obstetrics and Gynecology, 1983
The effect of ritodrine hydrochloride on hypoxic pulmonary vasoconstriction (HPV), the normal control mechanism for shunting blood flow away from nonventilated areas of the lung, was studied in nonpregnant dogs equipped with central monitors and electromagnetic flow probes. The systemic infusion of ritodrine at a dose of 4 micrograms/kg/min resulted in
W B, Conover, J L, Benumof, T C, Key
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Hypoxic Pulmonary Vasoconstriction – Invited Article

2009
Hypoxic pulmonary vasoconstriction (HPV) is an adaptive mechanism that in the face of localised alveolar hypoxia diverts blood away from poorly ventilated regions of the lung, thereby preserving ventilation/perfusion matching. HPV has been recognised for many years, but although the underlying mechanisms are known to reside within the arteries ...
Evans, A. Mark, Ward, Jeremy P. T.
openaire   +3 more sources

Hypoxic Pulmonary Vasoconstriction in Liver Cirrhosis

Chest, 1981
Impairment of hypoxic pulmonary vasoconstriction (HPV) is frequently cited as an explanation for the hypoxemia of liver cirrhosis. We investigated the pulmonary and systemic hemodynamic responses to acute inspiratory hypoxia, 12.5 percent oxygen in nitrogen during 10 minutes, in 24 patients with mildly to moderately decompensated liver cirrhosis and ...
Naeije, Robert, Hallemans, Roger, Mols, Pierre, Melot, Christian   +3 more
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Hypoxic and embolic pulmonary vasoconstriction

General Pharmacology: The Vascular System, 1983
In-vitro studies of helically-cut segmental pulmonary artery strips from 43 patients undergoing thoracic surgery were performed. Cumulative dose-response contraction curves were elicited, mean maximum contraction was significantly greater from histamine (Hist) than from prostaglandin F2 alpha (PGF2 alpha), serotonin (5-HT), angiotensin II (A II) or ...
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Hypoxic Pulmonary Vasoconstriction in Man: Effects of Hyperventilation

Acta Anaesthesiologica Scandinavica, 1985
The pulmonary vasoconstriction response to hypoxia was studied in eight anaesthetized supine subjects. One lung was made hypoxic while the other was ventilated with 100% oxygen. This was achieved by separating the tidal gas‐distribution to the lungs by means of a double‐lumen tracheal catheter.
L, Bindslev, A, Jolin-Carlsson, J, Santesson, I, Gottlieb   +3 more
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Vanadate potentiates hypoxic pulmonary vasoconstriction.

The Journal of Pharmacology and Experimental Therapeutics, 1991
Vanadate, an essential trace element and an inhibitor or stimulator of many enzymes, potentiates the hypoxic vasoconstriction in isolated lung preparations. However, the mechanism of action of vanadate in the lung circulation is unclear. We compared, in isolated rat lungs, the effect of vanadate (3 x 10(-5) M) on hypoxia-induced vasoconstriction with ...
N F, Voelkel, J, Czartolomna
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Hypoxic pulmonary vasoconstriction

Acta Anaesthesiologica Scandinavica, 1990
Michael Cutaia, Sharon Rounds
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Potassium channels modulate hypoxic pulmonary vasoconstriction

American Journal of Physiology-Lung Cellular and Molecular Physiology, 1998
The role of Ca2+-activated K+-channel, ATP-sensitive K+-channel, and delayed rectifier K+-channel modulation in the canine pulmonary vascular response to hypoxia was determined in the isolated blood-perfused dog lung. Pulmonary vascular resistances and compliances were measured with vascular occlusion techniques.
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