Results 61 to 70 of about 4,530 (250)
Clinical Features and Treatment Efficacy in Mutation-Related Epileptic Encephalopathy in the Infant [PDF]
Purpose Mutations in the cyclin-dependent kinase-like 5 (CDKL5) gene are associated with epileptic encephalopathy and severe cognitive impairment. We aim to characterize the association between this gene and treatment efficacy. Methods We retrospectively
Chung Mo Koo+6 more
doaj +1 more source
Interpretation of electroencephalography in infants
Aim: Based on published reports and our own observations, we aimed to assign the graphical elements of EEG into normal and abnormal groups and then identify up to five main graphic elements in each group to facilitate visual analysis and interpretation ...
A. G. Koshchavtsev, S. V. Grechanyi
doaj +1 more source
Brain Magnetic Resonance Imaging Findings in Infantile Spasms
Background: Infantile spasms are an age-specific epileptic disorder. They occur in infancy and early childhood. They can be caused by multiple etiologies. Structural abnormalities represent an important cause of infantile spasms. Brain magnetic resonance
Osama Y. Muthaffar
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ACTH Efficacy in Symptomatic Infantile Spasms
A retrospective evaluation of 26 case records of patients with diagnoses of symptomatic infantile spasms and classic hypsarrhythmia is reported from the Division of Pediatric Neurology, University of Minnesota Medical School, Minneapolis, MN.
J Gordon Millichap
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West Syndrome Remission Following Acute Viral Infection
Researchers at Nihon University School of Medicine, Tokyo, Japan, report 11 children with intractable epilepsy (West syndrome in 6 and myoclonic seizures in 5) who showed clinical and electrographic improvement following acute viral infection.
J Gordon Millichap
doaj +1 more source
Treatment of infantile spasms: emerging insights from clinical and basic science perspectives. [PDF]
Infantile spasms is an epileptic encephalopathy of early infancy with specific clinical and electroencephalographic (EEG) features, limited treatment options, and a poor prognosis.
Arnason, Barry GW+10 more
core +2 more sources
ACTH vs Vigabatrin in Infantile Spasms
The comparative efficacy and safety of ACTH (110 IU/m2 once daily for 15 days) and vigabatrin (100-150 mg/kg/daily in bid doses) was evaluated by a retrospective analysis of medical records of 42 infants (21 in each group) with infantile spasms and ...
J Gordon Millichap
doaj +1 more source
We report a novel case of an infant with neurofibromatosis type 1 (NF1) who presented with new onset presumed focal impaired awareness seizures with motor onset followed by rapid progression to infantile spasms (IS). Electroencephalography (EEG) captured
Shital H. Patel+3 more
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Abstract The accurate interpretation of scalp EEG remains an instrumental diagnostic component of epilepsy care. Knowledge of what constitutes normal EEG findings, non‐epileptiform abnormalities, and epileptiform patterns—both ictal and interictal—is essential for appropriate patient management.
Juan Luis Alcala‐Zermeno+9 more
wiley +1 more source
EEG biomarkers for the diagnosis and treatment of infantile spasms
Early diagnosis and treatment are critical for young children with infantile spasms (IS), as this maximizes the possibility of the best possible child-specific outcome.
Blanca Romero Milà+6 more
doaj +1 more source