Results 71 to 80 of about 96 (94)

Changes in motor unit conduction velocity after unilateral lower‐limb suspension and active recovery are correlated with muscle ion channel gene expression

open access: yesExperimental Physiology, EarlyView.
Abstract The effects of muscle disuse on the propagation of action potentials along motor unit (MU) muscle fibres, a key process for effective muscle activation and force generation, remain poorly understood. The aim of this study was to investigate changes in action potential propagation and to identify biological factors influencing these changes ...
Giacomo Valli   +12 more
wiley   +1 more source

Fragment Coverage: Unified Visualization and Quantitative Assessment of MS/MS Fragmentation Supports Metabolite Identification in Macromolecule Drug Metabolism Studies

open access: yesRapid Communications in Mass Spectrometry, Volume 40, Issue 21, 15 November 2026.
ABSTRACT Rationale Peptides and oligonucleotides are increasingly used as therapeutic agents, making the identification and structural elucidation of their metabolites a critical step in drug development. Liquid chromatography–mass spectrometry (LC‐MS/MS) is the primary analytical technique for this purpose; however, extensive backbone fragmentation ...
Paula Cifuentes   +3 more
wiley   +1 more source

The Effect of Culture Mix or Not Conflict Against the Decision Making—A fNIRS Study

open access: yesInternational Journal of Psychology, Volume 61, Issue 5, October 2026.
ABSTRACT With increasing globalisation and deepening integration of local cultures, a growing number of product advertisements incorporate diverse, mixed cultural elements, designed to attract consumer attention and enhance purchase interest. However, the underlying mechanisms by which visual stimuli successfully influence consumer purchase behaviour ...
Yanping He   +13 more
wiley   +1 more source

Professional Segmentation as a Barrier to Reform in Turkish Nursing

open access: yesNursing Inquiry, Volume 33, Issue 4, October 2026.
ABSTRACT This paper argues that segmentation within Turkish nursing is a major factor holding back the modernisation of nurse management. Since the millennium Türkiye's healthcare system has been transformed by NPM‐style reforms that changed financing mechanisms and strengthened aspects of performance management, but had only limited impact on nursing ...
Zuleyha Inceoz, David Hughes
wiley   +1 more source

Parvalbumin interneurons in Alzheimer's disease: Physiological insights and pathophysiological mechanisms

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Physiological and Pathological Alterations in PV+ Neurons: Under physiological conditions, PV+ interneurons exhibit fast‐spiking properties and generate gamma oscillations at the cost of high energy consumption. In AD, PV+ neurons display abnormalities in ion channels, dendrites, neurotransmission, energy metabolism, and neural oscillations, ultimately
Mengyan Wu   +5 more
wiley   +1 more source

The Role of Hippocampal Interneuron Migration in Neurodevelopmental Disorders: A Systematic Review

open access: yesHippocampus, Volume 36, Issue 5, September 2026.
ABSTRACT Hippocampal abnormalities are frequently associated with neurodevelopmental disorders as interneurons are crucial in establishing the network connectivity of neurons. This systematic review analyzed primary literature with a focus on aberrant hippocampal interneuron migration as an etiology for neurodevelopmental disorders, summarizing the ...
M. A. C. Till   +3 more
wiley   +1 more source

A Geometrically Regularized Gradient‐Damage Model With Orthogonality‐Based Energy Split for Dynamic Anisotropic Compression‐Shear Fracture

open access: yesInternational Journal for Numerical and Analytical Methods in Geomechanics, Volume 50, Issue 13, Page 5185-5212, September 2026.
ABSTRACT This study proposes a novel geometrically regularized gradient‐damage model for simulating dynamic mixed‐mode fracture in orthotropic materials with tension–compression asymmetry. In this model, a thermodynamic framework is formulated by incorporating damage dissipation into internal energy evolution, from which the constitutive relation and ...
Hui Li, Shanyong Wang
wiley   +1 more source

A Low‐Power Radioisotope XRF Spectrometer for Detection of Light Elements on Planetary Missions

open access: yesX-Ray Spectrometry, Volume 55, Issue 5, Page 721-729, September/October 2026.
ABSTRACT Current X‐ray spectrometers for in situ geochemical analysis on planetary missions typically rely either on X‐ray tubes, which demand electrical power and add mass and thermal complexity, or on alpha particle X‐ray spectrometers (APXS) that use rare 244 Cm sources, and come with severe concerns on radiation safety and isotope availability.
Leandro Silveri   +14 more
wiley   +1 more source

MtGRF8 interacts with MtSymCRK and prevents early bacteroid death during Medicago – Sinorhizobium symbiosis

open access: yesNew Phytologist, Volume 251, Issue 5, Page 2867-2887, September 2026.
MtSymCRK–MtGRF8‐14‐3‐3a, e, h and i functional model in R‐108 nodules. Summary In Medicago littoralis R‐108, Symbiotic CYSTEINE‐RICH RECEPTOR‐LIKE KINASE (MtSymCRK) is required to prevent defense reactions in symbiotic nodules during chronic infection.
Chaoyan Yin   +9 more
wiley   +1 more source

Contribution of One‐Electron Oxidation of Purine and Pyrimidine Bases to the Photo‐ and Radiation‐Induced Damage to Cellular DNA

open access: yesChemPhysChem, Volume 27, Issue 15, 14 August 2026.
One‐electron oxidation of purine and pyrimidine bases of isolated and cellular DNA generates related reactive base radical cations that are converted into final decomposition products through deprotonation and hydration. In the case of guanine, the most susceptible nucleobase to one‐electron oxidants, 8‐hydroxy‐7,8‐dihydroguanyl radical, thus formed by
Jean Cadet   +3 more
wiley   +1 more source

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