Results 51 to 60 of about 1,246,339 (259)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Comparison of the i-gelTM and the Laryngeal Mask Airway ClassicTM in terms of clinical performance
Revista Brasileira de Anestesiologia, 2015 PURPOSE: The i-gelTM is one of the second generation supraglottic airway devices. Our study was designed to compare the i-gel and the Laryngeal Mask Airway ClassicTM with respect to the clinical performance.METHODS: We compared the performance of the i ...
Reyhan Polat +5 more
doaj +1 more source
Dexmedetomidine infusion as an anesthetic adjuvant to general anesthesia for appropriate surgical field visibility during modified radical mastectomy with i-gel®: a randomized control study [PDF]
Korean Journal of Anesthesiology, 2016 BackgroundModified radical mastectomy is associated with appreciable blood loss, while endotracheal intubation leads to elevated hemodynamic responses. The present study aimed to evaluate the clinical efficacy of dexmedetomidine infusion as an anesthetic
Kumkum Gupta +5 more
doaj +1 more source
Comparison of clinical performance of the I-gel with LMA proseal
Journal of Anaesthesiology Clinical Pharmacology, 2013 To compare insertion characteristics of 2 different supraglottic devices [I-gel and Proseal laryngeal mask airway (PLMA)] and to observe any associated complications.This prospective, randomized study was conducted in 80 patients [Group I - I-gel insertion (n = 40) and Group P - LMA Proseal insertion (n =40)] of ASA grades I/II, of either sex in the ...
Gaurav Chauhan +5 more
openaire +3 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
i-gel insertion with modified jaw thrust technique
Indian Journal of Anaesthesia, 2015 Sir, Since the introduction of i-gel in modern anaesthesia practice, it is widely used by the anaesthesiologists, accident and emergency department personnel and in pre-hospital care setting. The reported first attempt success rate is 86%[1] with primary (manufacturer's recommended) insertion technique.
Kumar, Dileep +2 more
openaire +3 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Comparative Performance of I-Gel and Laryngeal Mask Airway Supreme: A Randomised, Controlled Study
Airway, 2019 Patients and Methods: In a randomised, controlled study, we compared the performance of i-gel against the laryngeal mask airway (LMA) Supreme in 60 anaesthetised and paralysed patients for non-laparoscopic surgical procedures.
B Uma +3 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Comparison of i-gel® and LMA Supreme® during laparoscopic cholecystectomy [PDF]
Korean Journal of Anesthesiology, 2015 BackgroundIn laparoscopic surgical procedures, many clinicians recommend supraglottic airway devices as good alternatives to intubation. We compared the i-gel® (i-gel) and LMA Supreme® (Supreme Laryngeal Mask Airway, SLMA) airway devices during ...
Sang Yoong Park +4 more
doaj +1 more source