Results 61 to 70 of about 1,215,139 (260)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Comparison of i-gel® and LMA Supreme® during laparoscopic cholecystectomy [PDF]
BackgroundIn laparoscopic surgical procedures, many clinicians recommend supraglottic airway devices as good alternatives to intubation. We compared the i-gel® (i-gel) and LMA Supreme® (Supreme Laryngeal Mask Airway, SLMA) airway devices during ...
Sang Yoong Park +4 more
doaj +1 more source
Comparison of clinical performance of the I-gel with LMA proseal
To compare insertion characteristics of 2 different supraglottic devices [I-gel and Proseal laryngeal mask airway (PLMA)] and to observe any associated complications.This prospective, randomized study was conducted in 80 patients [Group I - I-gel insertion (n = 40) and Group P - LMA Proseal insertion (n =40)] of ASA grades I/II, of either sex in the ...
Gaurav Chauhan +5 more
openaire +3 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
i-gel insertion with modified jaw thrust technique
Sir, Since the introduction of i-gel in modern anaesthesia practice, it is widely used by the anaesthesiologists, accident and emergency department personnel and in pre-hospital care setting. The reported first attempt success rate is 86%[1] with primary (manufacturer's recommended) insertion technique.
Kumar, Dileep +2 more
openaire +3 more sources
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Comparative Performance of I-Gel and Laryngeal Mask Airway Supreme: A Randomised, Controlled Study
Patients and Methods: In a randomised, controlled study, we compared the performance of i-gel against the laryngeal mask airway (LMA) Supreme in 60 anaesthetised and paralysed patients for non-laparoscopic surgical procedures.
B Uma +3 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Nuevos dispositivos supraglóticos
Introducción: El abordaje de la vía respiratoria ha evolucionado mucho en los últimos tiempos. Desde la Máscara laríngea convencional introducida por Brain a finales de la década de los 80 y hasta la fecha, se han utilizado otras alternativas como son el
Idoris Cordero Escobar
doaj +2 more sources

