Results 151 to 160 of about 16,736,389 (319)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Generalised MBER-based vector precoding design for multiuser transmission [PDF]

open access: yes, 2011
We propose a generalized vector precoding (VP) design based on the minimum bit error rate (MBER) criterion for multiuser transmission in the downlink of a multiuser system, where the base station (BS) equipped with multiple transmitting antennas ...
Chen, Sheng, Hanzo, Lajos, Yao, Wang
core  

More than Just Host Plant Preferences for the Two Main Vectors of Xylella fastidiosa in Europe: Two Insect Species and Two Different Behaviors

open access: yesInsects
Xylella fastidiosa is a vector-borne bacterium causing significant economic losses in global agricultural industries. Management strategies focus primarily on controlling vector populations.
Saúl Bernat-Ponce   +6 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Well-posed Vector Optimization Problems and Vector Variational Inequalities [PDF]

open access: yes
In this paper we introduce notions of well-posedness for a vector optimization problem and for a vector variational inequality of differential type, we study their basic properties and we establish the links among them.
Rocca Matteo
core  

On the geometry of rank two vector bundles and two-theta divisors on a curve [PDF]

open access: yes, 2003
This thesis aims at presenting results and remarks concerning the study of subvarieties of the projective space |2Ɵ| associated to a smooth projective curve C of genus at least 3 and its connections to the moduli space SU(_c)(2) of rank 2 semi-stable ...
Scataglini, Giovanna
core  

Coinfection of Two Rickettsia Species in a Single Tick Species Provides New Insight into Rickettsia-Rickettsia and Rickettsia-Vector Interactions. [PDF]

open access: yesMicrobiol Spectr, 2022
Pan YS   +21 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

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