Results 131 to 140 of about 16,736,389 (319)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Optimal E-Field Vector Combination for a Highly Focused Antenna-Array [PDF]

, 2014
A near-field highly focused circular phased-array antenna for 5.8-GHz radio frequency identification (RFID) applications is presented. The electric field (E-field) at the focus is enhanced by a constructive vector combination in a three-dimensional (3-D)
Perallos, Asier, Martinez, R, Sharma, A, Batchelor, John C., Garcia Zuazola, Ignacio Julio, de-Haro Ariet, L   +5 more
core   +1 more source

Immunolocalization of Beet Curly Top Virus (BCTV) and GroEL Chaperon Protein of Endosymbionts in Beet Leafhopper (Circulifer tenellus) Vector Tissue

Viruses
Beet curly top virus (BCTV, curtovirus, geminiviridae) causes one of the most economically significant viral diseases in crops in the Western United States and is transmitted only by the beet leafhopper (Circulifer tenellus) in a non-propagative ...
Batool M. Alkhatib, Samy Belteton, Rebecca Creamer   +2 more
doaj   +1 more source

Bacillus subtilis vector based oral rabies vaccines induced potent immune response and protective efficacy in mice. [PDF]

Front Microbiol, 2023
Zhang Y, Mo R, Sun S, Cui Z, Liang B, Li E, Wang T, Feng Y, Yang S, Yan F, Zhao Y, Xia X.   +11 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Cattle Zoonotic and Non-Zoonotic Tick-Borne Pathogens in Europe—A Retrospective Analysis of the Past 15 Years

Animals
Vector-borne diseases play a significant role in veterinary health, impacting both wild and domestic animals and posing a major constraint on the development of animal husbandry worldwide. The current study aimed to highlight some of the factors involved
Diana Hoffman, Ioan Cristian Dreghiciu, Ion Oprescu, Mirela Imre, Tiana Florea, Anamaria Plesko, Sorin Morariu, Marius Stelian Ilie   +7 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Insights on genomic profiles of drug resistance and virulence in a cohort of Leishmania infantum isolates from the Mediterranean area

Parasites & Vectors
Background Drug-resistant strains of Leishmania infantum challenge the effectiveness of treatments for clinical leishmaniosis and may lead to more frequent relapses.
Marina Carrasco-Martin, Joan Martí-Carreras, Marcel Gómez-Ponce, Maria Magdalena Alcover, Xavier Roura, Lluís Ferrer, Gad Baneth, Federica Bruno, Carmen Chicharro, Anabela Cordeiro-da-Silva, José Cristovão, Trentina Di Muccio, Carla Maia, Javier Moreno, Anabel Priego, Xavier Roca-Geronès, Nuno Santarem, Anna Vila Soriano, Fabrizio Vitale, Daniel Yasur-Landau, Olga Francino   +20 more
doaj   +1 more source

An Agrobacterium tumefaciens EHA105-Based GAANTRY Recipient Strain Generates High-Quality Transgenic Arabidopsis and Potato

Microorganisms
The GAANTRY (Gene Assembly in Agrobacterium by Nucleic acid Transfer using Recombinase technology) system enables efficient gene stacking within an Agrobacterium T-DNA. Using unidirectional site-specific recombinases and alternating selection markers, it
Upul Hathwaik, Leyla Hathwaik, Redeat Tibebu, Nic Nottingham, Teruko Oosumi, Troy Weeks, Roger Thilmony, James G. Thomson   +7 more
doaj   +1 more source

Silencing of ATP Synthase β Impairs Egg Development in the Leafhopper Scaphoideus titanus, Vector of the Phytoplasma Associated with Grapevine Flavescence Dorée. [PDF]

Int J Mol Sci, 2022
Ripamonti M, Cerone L, Abbà S, Rossi M, Ottati S, Palmano S, Marzachì C, Galetto L.   +7 more
europepmc   +1 more source