Results 111 to 120 of about 16,736,389 (319)

Seasonality influences key physiological components contributing to Culex pipiens vector competence. [PDF]

Front Insect Sci, 2023
Field EN, Smith RC.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Nonlinear support vector machines through iterative majorization and I-splines [PDF]

To minimize the primal support vector machine (SVM) problem, wepropose to use iterative majorization. To do so, we propose to use it-erative majorization. To allow for nonlinearity of the predictors, we use(non)monotone spline transformations.
Groenen, P.J.F., Bioch, J.C., Nalbantov, G.I.   +2 more
core   +1 more source

Beyond the Standard Model in Vector Boson Scattering Signatures [PDF]

, 2020
The high-energy scattering of massive electroweak bosons, known as vector boson scattering (VBS), is a sensitive probe of new physics. VBS signatures will be thoroughly and systematically investigated at the LHC with the large data samples available and ...
Gallinaro, Michele, Brivio,I, others
core  

Review of malaria situation in Cameroon: technical viewpoint on challenges and prospects for disease elimination

Parasites & Vectors, 2019
Malaria still has a devastating impact on public health and welfare in Cameroon. Despite the increasing number of studies conducted on disease prevalence, transmission patterns or treatment, there are to date, not enough studies summarising findings from
Christophe Antonio-Nkondjio, Cyrille Ndo, Flobert Njiokou, Jude D. Bigoga, Parfait Awono-Ambene, Josiane Etang, Albert Same Ekobo, Charles S. Wondji   +7 more
doaj   +1 more source

Multidimensional encoding of restricted and anisotropic diffusion by double rotation of the q vector. [PDF]

Magn Reson (Gott), 2023
Jiang H, Svenningsson L, Topgaard D.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Molecular genetic methods for quality control of inactivated vaccines using a Chikungunya virus model: vaccine strain identification and completeness of virus inactivation

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. The completeness of virus inactivation and the identity of the vaccine strain are essential parameters for the safety and quality of inactivated virus vaccines, which should be controlled during vaccine development and production. Currently,
A. S. Oksanich, T. G. Samartseva, K. V. Kaa, E. V. Otrashevskaia, A. G. Krasko, A. G. Laputina, N. A. Netesova, G. M. Ignatyev   +7 more
doaj   +1 more source

Dengue Incidence and Aedes Vector Collections in Relation to COVID-19 Population Mobility Restrictions. [PDF]

Trop Med Infect Dis, 2022
Surendran SN, Nagulan R, Tharsan A, Sivabalakrishnan K, Ramasamy R.   +4 more
europepmc   +1 more source